Results 111 to 120 of about 14,977,347 (337)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Integrated multiple sequence alignment [PDF]
Sammeth M. Integrated multiple sequence alignment. Bielefeld (Germany): Bielefeld University; 2005.The thesis presents enhancements for automated and manual multiple sequence alignment: existing alignment algorithms are made more easily accessible and ...
Sammeth, Michael
core
Multiple sequence alignment with the Divide-and-Conquer method. [PDF]
Stoye J. Multiple sequence alignment with the Divide-and-Conquer method. Gene. 1998;211(2):GC45-GC56.An improved algorithm for the simultaneous alignment of multiple protein and nucleic acid sequences, the Divide-and-Conquer Alignment procedure (DCA), is
Jens Stoye +1 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Non-isolated flexible interconnected distribution networks as the research object are explored, focusing on the adaptability issue of typical grounding fault detection methods when single-phase grounding faults occur in AC systems due to zero-sequence ...
Heming ZHANG +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
ON THE COMPONENTS OF SOME SPECIAL SEQUENCES
The Fibonacci, Lucas, Pell, Pell-Lucas, Jacobsthal and Jacobsthal-Lucas sequences {Fn}, {Ln}, {Pn}, {P Ln}, {Jn} and {JLn} are defined by two order recurrences for n ≥ 0, respectively, Fn+2 = Fn+1 + Fn, Ln+2 = Ln+1 + Ln, Pn+2 = 2Pn+1 + Pn, P Ln+2 = 2P Ln+1 + P Ln, Jn+2 = Jn+1 + 2Jn, JLn+2 = JLn+1 + 2JLn, with the initial conditions, respectively, F0 = 0,
Dişkaya, Orhan +2 more
openaire +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Performance of a Three-Phase Induction Motor under and over Unbalance Voltage
Voltage unbalance is an adverse global phenomenon impacting three-phase induction motor output. Three-phase source voltage may become imbalanced in a variety of respects, while a balanced system preserves stable voltage magnitude and angles in three ...
Abdulsatar H. Jassim +2 more
doaj

