Results 121 to 130 of about 3,098,423 (296)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Zhejiang dianliThe increasing penetration of distributed generation （DG） in distribution networks has exposed poor adaptation of conventional differential current protection schemes.
WU Zhenjie +6 more
doaj +1 more source
Ring element dynamic stresses [PDF]
The stresses in the CTRAPRG and CTRIARG ring elements are not calculated for any of the dynamic solutions in the current COSMIC version of NASTRAN. A DMAP alter sequence for Solution 8 and post-processing program, NASTPOST, are presented to calculate ...
Lambert, N., Tucchio, M.
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
IET Electric Power ApplicationsAiming at the technical problems of electromagnetic parameter analysis of large hydro generators, this paper innovatively proposes an electromagnetic torque analysis method based on the characteristics of fundamental electric quantity, with the core idea
Peng Hou, Guoguang Zhang, Baojun Ge
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
BuildingsPrecast concrete components have attracted a lot of attention due to their efficient production on off-site production lines. However, in the precast component production process, unreasonable production sequence and mold layout will reduce production ...
Junyong Liang +4 more
doaj +1 more source
Modelling the IRAS colors of galaxies [PDF]
A physical interpretation is proposed for the color-color diagram of galaxies which are powered only by star formation. The colors of each galaxy result from the combination of two components: cirrus-like emission from the neutral disk, and warmer ...
Helou, George
core +1 more source