Results 91 to 100 of about 3,422,913 (297)

An alternative method to the scrambled Halton sequence for removing correlation between standard Halton sequences in high dimensions [PDF]

open access: yes
Halton sequences were first introduced in the 1960s as an alternative to pseudo-random number sequences, with the aim of providing better coverage of the area of integration and negative correlation in the simulated probabilities between observations ...
Stephane Hess, John Polak
core  

Chromatic Dispersion Estimation Based on CAZAC Sequence for Optical Fiber Communication Systems

open access: yesIEEE Access, 2019
We propose a chromatic dispersion (CD) estimation method based on constant amplitude zero-autocorrelation (CAZAC) sequence and fractional Fourier transform (FrFT) algorithm for optical fiber communication systems, which extends the application of CAZAC ...
Feilong Wu   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Multiple sequence alignment accuracy and evolutionary distance estimation

open access: yesBMC Bioinformatics, 2005
Background Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pair wise sequence alignment, but this assumption has rarely been tested, and ...
Rosenberg Michael S
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

EbayesThresh: R Programs for Empirical Bayes Thresholding

open access: yesJournal of Statistical Software, 2005
Suppose that a sequence of unknown parameters is observed sub ject to independent Gaussian noise. The EbayesThresh package in the S language implements a class of Empirical Bayes thresholding methods that can take advantage of possible sparsity in the ...
Iain Johnstone, Bernard W. Silverman
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Integrating sequence composition information into microbial diversity analyses with k-mer frequency counting

open access: yesmSystems
k-mer frequency information in biological sequences is used for a wide range of applications, including taxonomy classification, sequence similarity estimation, and supervised learning. However, in spite of its widespread utility, k-mer counting has been
Nicholas A. Bokulich
doaj   +1 more source

Family-Based Haplotype Estimation and Allele Dosage Correction for Polyploids Using Short Sequence Reads

open access: yesFrontiers in Genetics, 2019
DNA sequence reads contain information about the genomic variants located on a single chromosome. By extracting and extending this information using the overlaps between the reads, the haplotypes of an individual can be obtained.
Ehsan Motazedi   +5 more
doaj   +1 more source

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