Results 91 to 100 of about 334,418 (265)
Channel Estimation for Two-Way Relay OFDM Networks
We consider the channel estimation for two-way relay OFDM networks. We proposed an LS-based channel estimation algorithm under block-based training schemes.
Yang Weiwei +3 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Task Loss Estimation for Sequence Prediction
Often, the performance on a supervised machine learning task is evaluated with a emph{task loss} function that cannot be optimized directly. Examples of such loss functions include the classification error, the edit distance and the BLEU score. A common workaround for this problem is to instead optimize a emph{surrogate loss} function, such as for ...
Dzmitry Bahdanau +6 more
openaire +2 more sources
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Polynomial estimation method for PN sequence based on reliability accumulation
The issues of insufficient efficiency and poor error-tolerance of current high-order polynomial estimation me-thods under error conditions were studied.By combining the iterative berlekamp-massey(BM)algorithm in GF(2)and the improved Chase algorithm,a ...
Song CHEN, Kai-zhi HUANG, Hua ZHAO
doaj +2 more sources
Research on Channel Estimation Algorithm based on LEO Satellite PCMA Signal
【Objective】With the development of the space-ground integrated information network, the Low Earth Orbit (LEO) satellite communication system is ushering in a development boom.
WANG Yuqi +3 more
doaj
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

