Results 111 to 120 of about 3,422,913 (297)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Channel Estimation for Two-Way Relay OFDM Networks
EURASIP Journal on Wireless Communications and Networking, 2010 We consider the channel estimation for two-way relay OFDM networks. We proposed an LS-based channel estimation algorithm under block-based training schemes.
Yang Weiwei +3 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Polynomial estimation method for PN sequence based on reliability accumulation
Tongxin xuebao, 2012 The issues of insufficient efficiency and poor error-tolerance of current high-order polynomial estimation me-thods under error conditions were studied.By combining the iterative berlekamp-massey(BM)algorithm in GF(2)and the improved Chase algorithm,a ...
Song CHEN, Kai-zhi HUANG, Hua ZHAO
doaj +2 more sources
, 2007 This paper investigates and compares the performance of various ultrawide bandwidth (UWB) systems when communicating over Nakagami-m fading channels. Specifically, the direct-sequence (DS), time-hopping (TH) and hybrid direct-sequence time-hopping (DS-TH)
Yang, Lie-Liang, Ahmed, Qasim Zeeshan
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Research on Channel Estimation Algorithm based on LEO Satellite PCMA Signal
Guangtongxin yanjiu【Objective】With the development of the space-ground integrated information network, the Low Earth Orbit (LEO) satellite communication system is ushering in a development boom.
WANG Yuqi +3 more
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