Results 101 to 110 of about 631,057 (304)
Nature CommunicationsDNA-Points Accumulation for Imaging in Nanoscale Topography (DNA-PAINT) enables multiplexed super-resolution imaging of biological samples. We expand the repertoire of speed-optimized DNA-PAINT sequences to visualize up to twelve targets in a sequential ...
Abhinav Banerjee +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Science Education International, 2017 This study explored the organization of contents in the junior secondary science curriculum of Bangladesh. The research questions of this study focus on how science content is sequenced and integrated in the intended curriculum.
Kalyani Bain +1 more
doaj +1 more source
Sequence organization of the ribosomal spacer ofD.melanogaster
Nucleic Acids Research, 1982 We subcloned several fragments of the rDNA nontranscribed spacer (NTS) of D.melanogaster and analysed their nucleotide sequence. The central portion contains a variable number of 240 base pair repeated sequences ending with two contiguous Alu I sites.
SIMEONE A +3 more
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Multidisciplinary HealthcareYinong Tian,1 Yixuan Cui,2 Xin Li,1 Su Liu,3 Yonggang Su1 1School of Foreign Languages and Literature, Shandong University, Jinan, Shandong, People’s Republic of China; 2The First Clinical Medical College, Guangzhou University of Chinese Medicine ...
Tian Y, Cui Y, Li X, Liu S, Su Y
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Sequence and organization of the Heliothis virescens ascovirus genome
Journal of General Virology, 2007 The nucleotide sequence of the Heliothis virescens ascovirus (HvAV-3e) DNA genome was determined and characterized in this study. The circular genome consists of 186 262 bp, has a G+C content of 45.8 mol% and encodes 180 potential open reading frames (ORFs).
Asgari, Sassan +4 more
openaire +5 more sources
Domain organization and sequence alignments.
, 2013 (A) Domain organization of pXqua [16], showing location of QUA1, KH and QUA2 regions in yellow blocks, and the boundaries of the QUA1 construct used in this work as a black line below.
Muzaffar Ali (387100) +1 more
core +1 more source