Results 181 to 190 of about 631,057 (304)

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Spatial and semantic memory reorganize a hippocampal long-axis gradient. [PDF]

Proc Natl Acad Sci U S A
Jordan AG, Voss JL, Kragel JE.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Folding the message: mRNA structure as a regulatory layer of human mitochondrial gene expression. [PDF]

Biochim Biophys Acta Mol Cell Res
Ahn A, Hong S, Brischigliaro M, Fontanesi F, Barrientos A.   +4 more
europepmc   +1 more source

Organization of the AKR Qa region [PDF]

, 1989
Steinmetz, M., Grosshaus, C., Messer, Gerald, Schwemmle, Sabine, Schmidt, Walter, Bevec, Dorian, Weiss, Elisabeth H.   +6 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Hierarchical Self-Organization of ABn Dendron-like Molecules into a Supramolecular Lattice Sequence

ACS Central Science, 2017
Xueyan Feng, Ruimeng Zhang, Yiwen Li, You-lee Hong, Dong Guo, Kening Lang, Kuan-Yi Wu, Mingjun Huang, Jialin Mao, Chrys Wesdemiotis, Yusuke Nishiyama, Wei Zhang, Wei Zhang, Toshikazu Miyoshi, Tao Li, Stephen Z. D. Cheng   +15 more
doaj   +1 more source

Genome Characterization of a Novel Hepe-like Virus and a Rhabdovirus Identified in <i>Macrosteles fascifrons</i>. [PDF]

Insects
Ge D, Ni Z, Wang J, Li Q, Jia Y, Wei X, Hu C, Fan R, Yang W, Lin S, Wu Z, Liu R, Xiao J.   +12 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The double histone fold: Structure, functional implications across the tree of life and relevance to protein design. [PDF]

Protein Sci
Ranaudo A, Miyake T, Cosentino U, Greco C.   +3 more
europepmc   +1 more source