Results 151 to 160 of about 2,885,310 (330)

Fine Sampling of Sequence Space for Membrane Protein Structural Biology. [PDF]

J Mol Biol, 2021
Loukeris M, Sanghai ZA, Vendome J, Hendrickson WA, Kloss B, Mancia F.   +5 more
europepmc   +1 more source

3-10 and Pi-Helices: Stochastic Events on Sequence Space; Reasons and Implications of their Accidental Occurrences across Protein Universe [PDF]

, 2009
Param Priya Singh, Anirban Banerji
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Individualized VDJ recombination predisposes the available Ig sequence space. [PDF]

Genome Res, 2021
Slabodkin A, Chernigovskaya M, Mikocziova I, Akbar R, Scheffer L, Pavlović M, Bashour H, Snapkov I, Mehta BB, Weber CR, Gutierrez-Marcos J, Sollid LM, Haff IH, Sandve GK, Robert PA, Greiff V.   +15 more
europepmc   +1 more source

Superoscillating Sequences Towards Approximation in $${\mathscr {S}}$$ S or $${\mathscr {S}}'$$ S ′ -Type Spaces and Extrapolation

, 2018
Fabrizio Colombo, Daniele C. Struppa, Alain Yger   +2 more
openalex   +2 more sources

Garling sequence spaces

, 2016
the paper has been replaced by the paper "On Garling Sequence spaces" by Albiac/Ansorena/Wallis: arXiv.org > math > arXiv:1703 ...
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta. [PDF]

MAbs, 2022
Schmitz S, Schmitz EA, Crowe JE, Meiler J.   +3 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope. [PDF]

PLoS Biol, 2022
Yoon J, Nekongo EE, Patrick JE, Hui T, Phillips AM, Ponomarenko AI, Hendel SJ, Sebastian RM, Zhang YM, Butty VL, Ogbunugafor CB, Lin YS, Shoulders MD.   +12 more
europepmc   +1 more source