Results 81 to 90 of about 660,133 (262)
On Some Properties of New Paranormed Sequence Space of Nonabsolute Type
We introduce some new generalized sequence space related to the space ℓ(𝑝). Furthermore we investigate some topological properties as the completeness, the isomorphism, and also we give some inclusion relations between this sequence space and some of the
Vatan Karakaya, Necip Şimşek
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
On r-duals of some difference sequence spaces [PDF]
In this paper we introduce and examine some properties of the sequence spaces C(mv, ,), C(mv, ,, C(mv, ,), Cmv, , and V(mv, ,), and compute the rα-, rβ- and r-duals of the sequence spaces ℓ(v), c(v) and c0(v), and the
Yavuz Altin, Mikail Et, Mahmut Isik
doaj
The Semi-Difference Entire Sequence Space 𝑐𝑠∩𝑑1
Let Γ denote the space of all entire sequences. Let Λ denote the space of all analytic sequences. In this paper, we introduce a new class of sequence space, namely, the semi-difference entire sequence space 𝑐𝑠∩𝑑1. It is shown that the intersection of all
N. Subramanian +2 more
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Relation of Morrey Sequence Spaces, Weak Type Morrey Sequence Spaces, and Sequence Spaces
Pragasto Aji Hendro Puadi +2 more
openaire +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source

