Results 201 to 210 of about 7,026,554 (307)

Genomic differences between sequence types 1 and 104 of Streptococcus suis Serotype 2. [PDF]

PeerJ, 2022
Kerdsin A, Takeuchi D, Akeda Y, Nakamura S, Gottschalk M, Oishi K.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Sequence Types and Antimicrobial Resistance Profiles of Salmonella Typhimurium in the Food Chain in Singapore. [PDF]

Microorganisms
Lim YC, Ong KH, Khor WC, Chua FYX, Lim JQ, Tan LK, Chen SL, Wong WK, Maiwald M, Barkham T, Koh TH, Khoo J, Chan JSH, Aung KT.   +13 more
europepmc   +1 more source

Molecular characterisation of Staphylococcus aureus in school-age children in Guangzhou: associations among agr types, virulence genes, sequence types, and antibiotic resistant phenotypes. [PDF]

BMC Microbiol, 2023
Cai H, Li X, Zhang C, Zhong H, Xie Y, Huang L, Zhang B, Long Y, Zhou Z, Liang B.   +9 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Molecular Analysis of Escherichia coli and Correlations Between Phylogroups and Sequence Types from Different Sources. [PDF]

Microorganisms
Soncini JGM, Koga VL, Fuga B, Tano ZN, Nakazato G, Kobayashi RKT, Lincopan N, Vespero EC.   +7 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Impact of <i>Pseudomonas aeruginosa</i> biofilm formation by different sequence types on treating lower limb vascular infections. [PDF]

Curr Res Microb Sci
Wang Y, Xiao Q, Yang Q, Long Y, Jiang Z, Zhang T, Hu Y, Gao B, Chen X, Wang T, Xiao L.   +10 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Antibiotic resistance and novel Sequence Types of <i>Klebsiella</i> spp. in human, animal, and food sources: a One Health perspective from Northern Nigeria. [PDF]

Curr Res Microb Sci
Adesoji AT, Mattioni Marchetti V, Cortimiglia C, Piscopiello F, Petrizzi I, Piazza A, Alabi ED, Cocconcelli PS, Migliavacca R.   +8 more
europepmc   +1 more source