Results 181 to 190 of about 3,761,412 (291)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Antibiotic resistance and novel Sequence Types of <i>Klebsiella</i> spp. in human, animal, and food sources: a One Health perspective from Northern Nigeria. [PDF]

Curr Res Microb Sci
Adesoji AT, Mattioni Marchetti V, Cortimiglia C, Piscopiello F, Petrizzi I, Piazza A, Alabi ED, Cocconcelli PS, Migliavacca R.   +8 more
europepmc   +1 more source

Characteristics of Streptococcus agalactiae causing urinary tract infections: Emergence of new sequence types ST74 and ST38 in Iran. [PDF]

Iran J Basic Med Sci, 2023
Razeghi M, Amini C, Fazeli M, Goudarzi M.   +3 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Molecular Analysis of Escherichia coli and Correlations Between Phylogroups and Sequence Types from Different Sources. [PDF]

Microorganisms
Soncini JGM, Koga VL, Fuga B, Tano ZN, Nakazato G, Kobayashi RKT, Lincopan N, Vespero EC.   +7 more
europepmc   +1 more source

Long-term exposure to food-grade disinfectants causes cross-resistance to antibiotics in Salmonella enterica serovar Typhimurium strains with different antibiograms and sequence types. [PDF]

Antimicrob Resist Infect Control, 2023
Wu-Chen RA, Feng J, Elhadidy M, Nambiar RB, Liao X, Yue M, Ding T.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Distribution of Clostridioides difficile ribotypes and sequence types across humans, animals and food in 13 European countries. [PDF]

Emerg Microbes Infect
Rupnik M, Viprey V, Janezic S, Tkalec V, Davis G, Sente B, Devos N, Muller BH, Santiago-Allexant E, Cleuziat P, Wilcox M, Davies K, COMBACTE-CDI consortium.   +12 more
europepmc   +1 more source

Recurrent E. coli Urinary Tract Infections in Nursing Homes: Insight in Sequence Types and Antibiotic Resistance Patterns. [PDF]

Antibiotics (Basel), 2022
Hidad S, van der Putten B, van Houdt R, Schneeberger C, Kuil SD.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source