Memory Capacity for Sequences in a Recurrent Network with Biological Constraints [PDF]
The CA3 region of the hippocampus is a recurrent neural network that is essential for the storage and replay of sequences of patterns that represent behavioral events.
Christian Leibold +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Seasonal Diversity of Endophytic Bacteria Associated with Cinnamomum camphora (L.) Presl.
Investigations on the density, diversity, and distribution of endophytic bacterial community associated with leaves of Cinnamomum camphora (L.) Presl. were carried out during three seasons using 16s rDNA high-throughput sequencing technology.
Abubakr Abdelwhab Hamd Elmagzob +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Formation of task representations and replay in mouse medial prefrontal cortex
The medial prefrontal cortex (mPFC) is thought to support cognitive flexibility by forming and maintaining generalized representations of abstract tasks.
Hamed Shabani +5 more
doaj +1 more source
DNA sequences classification and computation scheme based on the symmetry principle [PDF]
The DNA sequences containing multifarious novel symmetrical structure frequently play crucial role in how genomes work. Here we present a new scheme for understanding the structural features and potential mathematical rules of symmetrical DNA sequences ...
Xiao-Gang Song, Wen-Yuan Qiu
core
Smarandache Sequences: Explorations and Discoveries with a Computer Algebra System [PDF]
We study Smarandache sequences of numbers, and related problems, via a Computer Algebra System.
Gouveia, Paulo D. F. +1 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
This study investigates the seismic performance of two-, four-, and six-story composite buildings equipped with viscous wall dampers, focusing on structures with concrete-filled steel tubular (CFST) columns and steel beams. Through nonlinear time history
Panagiota Katsimpini
doaj +1 more source
Porcine Rotavirus Closely Related to Novel Group of Human Rotaviruses
We determined nucleotide sequences and inferred amino acid sequences of viral protein (VP) 4, VP6, VP7, and nonstructural protein 4 genes of a porcine rotavirus strain (SKA-1) from Japan. The strain was closely related to a novel group of human rotavirus
Mitsutaka Wakuda +6 more
doaj +1 more source

