Results 81 to 90 of about 3,116,462 (307)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Another Set of Sequences, Sub-Sequences, and Sequences of Sequences

open access: yes, 2000
In this paper 101 new integer sequences, sub-sequences, and sequences of sequences, together with related unsolved problems and conjectures, are presented. Also, definitions, examples, solved or open questions, and references for each sequence are given.
openaire   +2 more sources

The Protist Ribosomal Reference database (PR2): a catalog of unicellular eukaryote Small Sub-Unit rRNA sequences with curated taxonomy [PDF]

open access: yes, 2012
The interrogation of genetic markers in environmental meta-barcoding studies is currently seriously hindered by the lack of taxonomically curated reference data sets for the targeted genes.
Probert, Ian   +35 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Exceptional Sequences over Graded Cohen-Macaulay Rings [PDF]

open access: yes, 1999
The concept of exceptional sequences was developed by Gorodentsev and Rudakov in [3] and generalized by Bondal in [1].
Tokuji Araya, Araya, Tokuji
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Missed detections of influenza A(H1)pdm09 by real-time RT–PCR assay due to haemagglutinin sequence mutation, December 2017 to March 2018, northern Viet Nam

open access: yesWestern Pacific Surveillance and Response, 2019
Introduction: There are two methods of reverse transcription polymerase chain reaction (RT–PCR) that have been the common methods to detect influenza infections: conventional and real-time RT–PCR.
Hoang Vu Mai Phuong   +9 more
doaj   +1 more source

$A$-sequences, $Z$-sequence, and $B$-sequences of Riordan Matrices

open access: yesDiscret. Math., 2019
We defined two type $B$-sequences of Riordan arrays and present the $A$-sequence characterization and $Z$-sequence characterization of the Riordan matrices with two type $B$-sequences. The subgroups characterized by $A$-sequences and $Z$-sequences are studied.
openaire   +4 more sources

Integrality and the Laurent phenomenon for Somos 4 and Somos 5 sequences [PDF]

open access: yes, 2008
Somos 4 sequences are a family of sequences defined by a fourth-order quadratic recurrence relation with constant coefficients. For particular choices of the coefficients and the four initial data, such recurrences can yield sequences of integers.
Swart, Christine, Hone, Andrew N.W.
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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