Results 61 to 70 of about 16,735 (263)
Journal of Advanced Mechanical Design, Systems, and ManufacturingTorque performance is one of the main factors to consider in motor design. To obtain desirable torque performance, torque ripple must be considered as well as average torque.
Tatsuya ASANUMA, Yoshihiro KANNO
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Dynamic Optimal Control of a One-Dimensional Magnetohydrodynamic System With Bilinear Actuation
IEEE Access, 2018 The manipulation of the magnetic field has been a proven effective method to change the flow velocity in magnetohydrodynamics (MHD) flow systems. In this paper, we consider a novel bilinear magnetic control problem arising in a 1-D MHD flow system ...
Zhigang Ren +3 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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MetalsThe axle bridge plays a crucial role in the bogie of low-floor light rail vehicles, impacting operational efficiency and fuel economy. To minimize the total cost of the structure and turning of axle bridges, an optimization model of structural and ...
Xiaoke Li +8 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
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OPTIMAL SYNTHESIS OF A MANIPULATOR USING TWO COMPETITIVE METHODS
Facta Universitatis. Series: Mechanical Engineering, 2014 This paper defines a program realization for finding the optimal geometry of a planar Z-mechanism. The paper shows the mathematical procedure for defining the objective function, the constraint function and the search fields which are used for solving ...
Jovan Pavlović +2 more
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
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