Results 71 to 80 of about 163,780 (214)
Sequential Kernel Herding: Frank-Wolfe Optimization for Particle Filtering [PDF]
, 2015 Recently, the Frank-Wolfe optimization algorithm was suggested as a procedure to obtain adaptive quadrature rules for integrals of functions in a reproducing kernel Hilbert space (RKHS) with a potentially faster rate of convergence than Monte Carlo ...
Bach, Francis +2 more
core +3 more sources
Sequential Sampling for Optimal Weighted Least Squares Approximations in Hierarchical Spaces [PDF]
SIAM Journal on Mathematics of Data Science, 2019 We consider the problem of approximating an unknown function $u\in L^2(D, )$ from its evaluations at given sampling points $x^1,\dots,x^n\in D$, where $D\subset \mathbb{R}^d$ is a general domain and $ $ is a probability measure. The approximation is picked in a linear space $V_m$ where $m=\dim(V_m)$ and computed by a weighted least squares method ...
Arras, Benjamin +2 more
openaire +4 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 2018 In this paper, we propose a successive convex approximation framework for sparse optimization where the nonsmooth regularization function in the objective function is nonconvex and it can be written as the difference of two convex functions. The proposed
Chatzinotas, Symeon +3 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
MetalsThe axle bridge plays a crucial role in the bogie of low-floor light rail vehicles, impacting operational efficiency and fuel economy. To minimize the total cost of the structure and turning of axle bridges, an optimization model of structural and ...
Xiaoke Li +8 more
doaj +1 more source
Variational Sequential Monte Carlo
, 2018 Many recent advances in large scale probabilistic inference rely on variational methods. The success of variational approaches depends on (i) formulating a flexible parametric family of distributions, and (ii) optimizing the parameters to find the member
Blei, David M. +3 more
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
OPTIMAL SYNTHESIS OF A MANIPULATOR USING TWO COMPETITIVE METHODS
Facta Universitatis. Series: Mechanical Engineering, 2014 This paper defines a program realization for finding the optimal geometry of a planar Z-mechanism. The paper shows the mathematical procedure for defining the objective function, the constraint function and the search fields which are used for solving ...
Jovan Pavlović +2 more
doaj