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Sequential Estimation and Closed Sequential Decision Procedures
The Annals of Mathematical Statistics, 1964 In Chapter 10 of his classical work on sequential analysis [8], Wald started a program for dealing with multiple decision problems based on sequential estimation, and this work was to some extent further developed by Stein [7]. However, as far as the present writer is aware, this program was never completed. In a recent paper [6] a sequential procedure
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Reducing sequential change detection to sequential estimation
, 2023 11 ...
Shekhar, Shubhanshu, Ramdas, Aaditya
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
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Sequential Point Estimation of a Function of the Exponential Scale Parameter
Austrian Journal of Statistics, 2016 We consider sequential point estimation of a function of the scale parameter of an exponential distribution subject to the loss function given as a sum of the squared error and a linear cost.
Chikara Uno +2 more
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Identification and Estimation of Stochastic Bargaining Models, Third Version [PDF]
Stochastic sequential bargaining models (Merlo and Wilson (1995, 1998)) have found wide applications in different fields including political economy and macroeconomics due to their flexibility in explaining delays in reaching an agreement.
Antonio Merlo, Xun Tang
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
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Psychophysics and the judgment of price [PDF]
Judgment and Decision Making, 2009 When participants in psychophysical experiments are asked to estimate or identify stimuli which differ on a single physical dimension, their judgments are influenced by the local experimental context --- the item presented and judgment made on the ...
William J. Matthews, Neil Stewart
doaj
New Journal of Physics, 2017 A major challenge facing existing sequential Monte Carlo methods for parameter estimation in physics stems from the inability of existing approaches to robustly deal with experiments that have different mechanisms that yield the results with equivalent ...
Christopher Granade, Nathan Wiebe
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