Results 111 to 120 of about 540,179 (287)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Sequential Estimation Saving Sampling Operations

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1983
SUMMARY A method is proposed for accelerating the sequential estimation procedure due to Anscombe, Chow and Robbins. It enables the number of sampling operations to be reduced by any predetermined factor, at the expense of only a slight increase in the expected sample size.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A flexible framework for sequential estimation of model parameters in computational hemodynamics. [PDF]

open access: yesAdv Model Simul Eng Sci, 2020
Arthurs CJ   +4 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Semiblind estimation of MIMO time-varying channels based on sequential importance resampling algorithm

open access: yes上海师范大学学报. 自然科学版, 2013
Particle filtering can be used to handle the non-liner and non-Gaussian problems,while the sequential importance resampling (SIR) algorithm can be better to solve the degeneracy phenomenon in particle filtering and be applied in the semiblind estimation ...
SHI Danfeng, ZHANG Jing
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

СOMPUTATIONAL COMPLEXITY ANALYSIS OF RECURRENT DATA PROCESSING ALGORITHMS IN OPTICAL COHERENCE TOMOGRAPHY [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2014
The paper deals with the basic principles of signals representation in optical coherence tomography with the usage of dynamic systems theory formalism.
Maxim A. Volynsky   +3 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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