Results 101 to 110 of about 49,380 (287)
Shaping Student Relationships: The Role of Personality in Early Childhood Pre-Service Teachers
Behavioral SciencesThe purpose of this explanatory sequential mixed-methods study is to explain teacher–student relationships in preschool classrooms in terms of the child’s temperament and the pre-service preschool teachers’ personalities.
Seda Ata, İlayda Kimzan
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Mixed Methods Research as Third Methodological Movement:
جامعه شناسی کاربردی, 2010 Mixed Method Research is considered as the latest methodological orientation in social and behavioralsciences and sociology which has been developed following a long period of intra-paradigm controversiesbetween quantitative and qualitative approaches ...
Ahmad Mohammadpour +2 more
doaj
Social Sciences and Humanities OpenIndividual decision-making is crucial for rural homeowners to adopt solar home systems (SHS). Currently, SHS adoption in South Africa is slow and disappointing. Individuals choose to adopt or reject a SHS at the household level.
Ranganai Chidembo +2 more
doaj +1 more source
, 2019 This paper presents an exploratory sequential mixed methods approach in validating the Economics Placement Test [EPT] to assess prospective undergraduates’ Economics knowledge and perceived skills for admission into undergraduate programmes of Nigerian ...
Bichi, A. A. +4 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2014 This paper describes the use of exploratory focus groups to inform the development of a survey instrument in a\ud sequential phase mixed methods study investigating differences in secondary students’ career choice\ud capability.
Galliott, Natal'ya, Graham, Linda J.
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Optimization techniques with knowledge based control in ship concept design
, 1990 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An integrated computational approach to Ship Concept Design using optimization techniques and a knowledge base to control the optimization process has been ...
Schachter, Richard David, Schachter, R.D
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source