Results 111 to 120 of about 49,380 (287)

Development and Validation of a Cultural and Linguistic Diversity Scale to Measure Pre-service EFL Teachers’ Self-Efficacy Beliefs

SAGE Open
The study aims to develop and validate an affordable and generalizable survey design tool to measure pre-service EFL teachers’ self-efficacy beliefs about cultural and linguistic diversity.
Melih Kırcalı, Kürşat Cesur
doaj   +1 more source

Constructing a relationship model of influencing factors to optimize the implementation of blended learning: an exploratory sequential design

, 2023
Objective: During the COVID-19 pandemic, Chinese secondary schools embraced the practice of blended learning (BL) on a large scale. Although secondary school teachers are aware of BL’s potential benefits in improving student-learning outcomes, its ...
Lin, Wang, Omar, Muhd Khaizer, Zakaria, Noor Syamilah, Zulkifli, Nurul Nadwa   +3 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Online learners’ readiness and learning interactions: A sequential analysis

, 2018
15th International Conference on Cognition and Exploratory Learning in the Digital Age, CELDA 2018 -- 21 October 2018 through 23 October 2018 -- 143177An important advantage of e-learning environments is the numerical observation of the learning ...
Keskin S., Yurdugül H., Şahin M.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Exploratory sequential mixed-methods design in transitional justice research: a methodological research note from Portugal

Os académicos e interessados em justiça transicional (jt) reconhecem cada vez mais a impor tância de estudar as atitudes das vítimas face a políticas de reparação, retribuição e homenagem. Contudo, a recolha de dados sobre atitudes em relação à jt entre vítimas de repressão enfrenta desafios, sobretudo após regimes de longa duração.
Serra-Silva, Sofia, Filipa, Raimundo
openaire   +5 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Construction and validation of a Computerized Formative Assessment Literacy (CFAL) questionnaire for language teachers: an exploratory sequential mixed-methods investigation

Language Testing in Asia
The contributions of Computerized Formative Assessment (CFA) to teachers’ instructional practices and students’ learning outcomes necessitate the development of valid and reliable instruments for measuring teachers’ literacy.
Golnoush Haddadian, Sadaf Radmanesh, Nooshin Haddadian   +2 more
doaj   +1 more source

Sensitivity analysis and related analysis: A survey of statistical techniques

This paper reviews the state of the art in five related types of analysis, namely (i) sensitivity or what-if analysis, (ii) uncertainty or risk analysis, (iii) screening, (iv) validation, and (v) optimization. The main question is: when should which type
Kleijnen, J.P.C.
core