Results 61 to 70 of about 212,365 (278)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Use of mixed methods designs in substance research: a methodological necessity in Nigeria [PDF]

, 2013
The utility of mixed methods (qualitative and quantitative) is becoming increasingly accepted in health sciences, but substance studies are yet to substantially benefit from such utilities.
A Adewuya, A Atkinson, A Bryman, A Bryman, A Bryman, A Dimah, A Klein, A Odenigbo, A Tashakkori, AB Makanjuola, AJ Onwuegbuzie, AO Adewuya, BA Ikuesan, BO Olley, C Teddlie, C Teddlie, CM Woolley, D Freshwater, D Silverman, DA Dawson, DL Morgan, DM Mertens, DT Campbell, E Dumbili, EIC Chikere, Emeka W. Dumbili, EP Stoller, F Measham, FG Castro, FM Moghaddam, GE Abikoye, GE Abikoye, H Wechsler, I Newman, I Obot, J Abdulmalik, J Demant, J Demant, J Wheeldon, J Østergaard, JC Greene, JC Greene, JF Molina-Azorin, JM Morse, JMF Guise, JR Vicary, JW Creswell, JW Creswell, KM Collins, KR Howe, L Brener, LM Coleman, M Denscombe, MG Piacentini, NK Denzin, NL Leech, O Abayomi, OA Odejide, OG Oshodin, OO Umoh, P Bazeley, R Goodwin, RB Johnson, RB Johnson, RB Johnson, RK Yin, S Wemm, TD Jick, VL Plano Clark   +68 more
core   +1 more source

An Exploratory Sequential Mixed Methods Design to Identify Criteria for Continuous Performance Evaluation

European Conference on Research Methodology for Business and Management Studies, 2023
An alternative to the ubiquitous annual performance evaluation is continuous performance evaluation that is posed to give more objective, frequent and constructive feedbacks. Despite researchers recommending following a continuous performance evaluation for employees, there are hardly any progress in this regard. One of the hindrances is in identifying
openaire   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The organizational climate and its impact on the motivation of Human Talent

Revista Arbitrada Interdisciplinaria Koinonía, 2019
The human talent is the main element of an organization, where Work Climate and motivation are fundamental to the success and achievement of its objectives. Problems precisely identified in the Unit of analysis of the present investigation.
Diana Elizabeth Valencia Naranjo, Juan Carlos Erazo Álvarez, Cecilia Ivonne Narváez Zurita   +2 more
doaj   +1 more source

When is an exploration exploratory?  A comparative analysis of geometry lessons [PDF]

, 2018
This paper presents a comparative analysis of two textbook lessons on the same topic from U.S. textbooks to learn how differently - designed “exploratory” lessons may structure content to enable or constrain student inquiry. One lesson, representative of
Dietiker, Leslie, Richman, Andrew
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Leadership capability of team leaders in construction industry [PDF]

, 2013
This research was conducted to identify the important leadership capabilities for Malaysia construction industry team leaders. This research used exploratory sequential mix-method research design which is qualitative followed by quantitative research
Wan Muda, Wan Hanim Nadrah
core  

Ringo: Interactive Graph Analytics on Big-Memory Machines [PDF]

, 2015
We present Ringo, a system for analysis of large graphs. Graphs provide a way to represent and analyze systems of interacting objects (people, proteins, webpages) with edges between the objects denoting interactions (friendships, physical interactions ...
Banerjee, Arijit, Leskovec, Jure, Perez, Yonathan, Puttagunta, Rohan, Raison, Martin, Shah, Pararth, Sosic, Rok   +6 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source