Results 71 to 80 of about 212,365 (278)

Study Protocol for Investigating Physician Communication Behaviours that Link Physician Implicit Racial Bias and Patient Outcomes in Black Patients with Type 2 Diabetes Using an Exploratory Sequential Mixed Methods Design [PDF]

, 2018
Introduction Patient-physician racial discordance is associated with Black patient reports of dissatisfaction and mistrust, which in turn are associated with poor adherence to treatment recommendations and underutilisation of healthcare. Research further
Fetters, Michael D., Hagiwara, Nao, Lafata, Jennifer Elston, Mezuk, Briana, Vrana, Scott R   +4 more
core   +1 more source

The Role of Qualitative Research in Clinical Trial Development: The EASE Back Study [PDF]

, 2018
This article outlines the rationale for adopting a mixed methods approach within randomized controlled trials (RCTs) and explores challenges associated in doing so.
Barlas, Panos, Bartlam, Bernadette, Bishop, Annette, Foster, Nadine E., Holden, Melanie A., Ismail, Khaled M., KETTLE, Christine, Waterfield, Jacqueline   +7 more
core   +1 more source

DEVELOPMENT AND VALIDATION OF A MULTI-EXERCISE DESIGN (MXD) COMMITMENT SCALE: AN EXPLORATORY SEQUENTIAL DESIGN

European Journal of Physical Education and Sport Science
The study aimed to develop a context-specific scale to measure the fitness enthusiasts' commitment to exercise in regions XI and XII using a multi-exercise design (MXD) fitness program. The study employed a mixed-methods approach, specifically the exploratory sequential design.
Wilfredo M. Atayan, Porferia S. Poralan
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Stochastic Database Cracking: Towards Robust Adaptive Indexing in Main-Memory Column-Stores [PDF]

, 2012
Modern business applications and scientific databases call for inherently dynamic data storage environments. Such environments are characterized by two challenging features: (a) they have little idle system time to devote on physical design; and (b ...
Halim, Felix, Idreos, Stratos, Karras, Panagiotis, Yap, Roland H. C.   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Addressing the learners' needs for specific and constructive feedback [PDF]

, 2010
This paper discusses an on-going project which proposes to make feedback to students more personal, explicit and more useful as a method of further engaging students.
Perera, Noel, Tudor, Jenna
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Criteria for the definition of indicators in architectural learning in the Design Studio through the use of the e-portfolio

Journal of Architecture and Urbanism, 2020
The objective of this research is to identify, within the context of teaching-learning through the Design Studio, factors and criteria which may support the construction of architectural indicators of learning in students.
Miguel Roco, Elena Barberà
doaj   +1 more source