Results 111 to 120 of about 448,986 (305)

Counterbalancing for serial order carryover effects in experimental condition orders [PDF]

open access: yes, 2012
Reactions of neural, psychological, and social systems are rarely, if ever, independent of previous inputs and states. The potential for serial order carryover effects from one condition to the next in a sequence of experimental trials makes ...
Brooks, Brooks, Joseph L
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Aspects of aspects: On Harvey Sacks’s “Missing” book, Aspects of the sequential organization of conversation (1970)

open access: yes, 2005
Conversation analysis (CA) is now what Kuhn once called a normal science. It has a discernible body of concepts, methods, and recognizable objects of analysis.
McHoul, A.
core  

Sequential order and spaces 𝑆_{𝑛}

open access: yes, 1976
It is shown that the space ψ ∗ {\psi ^{\ast }} is a sequential space of order 2 2 which does not contain a copy of S 2
M. Rajagopalan
core   +1 more source

Multitask-Based Anti-Collision Trajectory Planning of Redundant Manipulators

open access: yesBiomimetics
During performing multiple tasks of a redundant manipulator, the obstacles affect the sequential order of task areas and the joint trajectories. The end-effector is constrained to visit multiple task areas with an optimal anti-collision path, while the ...
Suping Zhao   +4 more
doaj   +1 more source

On the Endogenous Order of Play in Sequential Games

open access: yesSSRN Electronic Journal
We formalize, under the name of games of addition, the strategic interaction between agents that can play non-simultaneously by adding payoff relevant actions to those that any other players or themselves have already taken previously, but may also agree unanimously to stop adding them and collect the payoffs associated with the truncated sequence of ...
Barberà, Salvador, Gerber, Anke
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Sequential decisions in allocation problems

open access: yes
In the context of cooperative TU-games, and given an order of players, we consider the problem of distributing the worth of the grand coalition as a sequential decision problem.
Josep Maria Izquierdo Aznar   +2 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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