Results 101 to 110 of about 448,986 (305)
On optimality of kernels for approximate Bayesian computation using sequential Monte Carlo
, 2011 Approximate Bayesian computation (ABC) has gained popularity over the past few years for the analysis of complex models arising in population genetics, epidemiology and system biology.
Barnes, C +7 more
core
A note on exponentially bounded stopping times of certain one-sample sequential rank order tests
International Journal of Mathematics and Mathematical Sciences, 1985 A simple proof of the exponential boundedness of the stopping time of the one-sample sequential probability ratio tests (SPRT's) is obtained.
Z. Govindarajulu
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Sequential decision problems, dependently typed solutions
, 2013 We propose a dependently typed formalization for a simple class of sequential decision problems. For this class of problems, we im- plement a generic version of Bellman's backwards induction algorithm [2] and a machine checkable proof that the proposed ...
Botta, Nicola +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Sequential Sharing Rules for River Sharing Problems [PDF]
We analyse the redistribution of a resource among agents who have claims to the resource and who are ordered linearly. A well known example of this particular situation is the river sharing problem.
Hans-Peter Weikard, Erik Ansink
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Maximizing Revenue in Sequential Auctions
, 2007 We study sequential auctions for private value objects and unit-demand bidders using second-price sealed-bid rules. We analyze this scenario from the seller's perspective and consider several approaches to increasing the total revenue.
Edith Elkind +3 more
core
Frontiers in MicrobiologyArnA and ArnB serve as regulators within the Sulfolobus archaellum regulatory network by modulating the archaellum components ArlB and ArlX, which are essential for swimming motility.
Mohamed Watad +14 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source