Results 71 to 80 of about 448,986 (305)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Mechanisms for the generation and regulation of sequential behaviour

, 2003
A critical aspect of much human behaviour is the generation and regulation of sequential activities. Such behaviour is seen in both naturalistic settings such as routine action and language production and laboratory tasks such as serial recall and many ...
Cooper, Richard P.
core   +1 more source

A sequential regularization method for time-dependent incompressible Navier--Stokes equations [PDF]

, 1997
The objective of the paper is to present a method, called the sequential regularization method (SRM), for the nonstationary incompressible Navier--Stokes equations from the viewpoint of regularization of differential-algebraic equations (DAEs), and to ...
Lin, Ping
core   +1 more source

Sequential choice in ordered bundles

Experience goods such as sporting and artistic events, songs, videos, news stories, podcasts, and television series, are often packaged and consumed in bundles. Many such bundles are ordered in the sense that the individual items are consumed sequentially, one at a time.
Rajeev Kohli, Kriste Krstovski, Hengyu Kuang, Hengxu Lin   +3 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Convergence of the SMC implementation of the PHD filter [PDF]

, 2005
The probability hypothesis density (PHD) filter is a first moment approximation to the evolution of a dynamic point process which can be used to approximate the optimal filtering equations of the multiple-object tracking problem.
Singh, Sumeetpal S. (Sumeetpal Sidhu), Vo, Ba-Ngu, Johansen, Adam M., Singh, SS, Doucet, Arnaud, Doucet, A, Vo, B, Vo, B-N, ,, Johansen, AM   +9 more
core   +1 more source

Fractional-Order Sequential Linear Differential Equations with Nabla Derivatives on Time Scales

Axioms
In this paper, we present a general theory for fractional-order sequential differential equations with Riemann–Liouville nabla derivatives and Caputo nabla derivatives on time scales.
Cheng-Cheng Zhu, Jiang Zhu
doaj   +1 more source

Basic Results for Sequential Caputo Fractional Differential Equations

Mathematics, 2015
We have developed a representation form for the linear fractional differential equation of order q when 0 < q < 1, with variable coefficients.
Bhuvaneswari Sambandham, Aghalaya S. Vatsala   +1 more
doaj   +1 more source