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Single-molecule and single-nanoparticle SERS: from fundamental mechanisms to biomedical applications

Chemical Society Reviews, 2008
This tutorial review discusses a new class of colloidal metal nanoparticles that is able to enhance the efficiencies of surface-enhanced Raman scattering (SERS) by as much as 10(14)-10(15) fold. This enormous enhancement allows spectroscopic detection and identification of single molecules located on the nanoparticle surface or at the junction of two ...
X-M, Qian, S M, Nie
openaire   +2 more sources

Fundamental studies of surface-enhanced Raman scattering (SERS) using aerosolized substrates

SPIE Proceedings, 2012
The research presented in this paper improves potential for the application of surface-enhanced Raman scattering (SERS) in remote detection and analysis. Remote (stand-off) Raman sensing, with its ability to "fingerprint" analyte based on their unique vibrational spectra, offers great potential to address the challenging analytical problem of ...
Obie Okponyia   +3 more
openaire   +1 more source

Recent Developments in SERS Microfluidic Chips: From Fundamentals to Biosensing Applications

ACS Applied Materials & Interfaces
This paper reviews the latest research progress of surface-enhanced Raman spectroscopy (SERS) microfluidic chips in the field of biosensing. Due to its single-molecule sensitivity, selectivity, minimal or no preprocessing, and immediacy, SERS is considered a promising biosensing technology.
Shuai Lian, Xiaoqiong Li, Xuefei Lv
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ChemInform Abstract: SERS as a Bioassay Platform: Fundamentals, Design, and Applications

ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Marc D. Porter   +4 more
openaire   +1 more source

A review of cellulose-based substrates for SERS: fundamentals, design principles, applications

Cellulose, 2019
Surface enhanced Raman spectroscopy (SERS) provides a useful sensory platform whereby target molecules at low concentration are identified, potentially detecting a single molecule. As a result, SERS has been widely applied in a variety of research endeavors using different substrates, one of which is a cellulose-based substrate.
Segun A. Ogundare, Werner E. van Zyl
openaire   +1 more source

Fundamental studies on enhancement and blinking mechanism of surface-enhanced Raman scattering (SERS) and basic applications of SERS biological sensing

Frontiers of Physics, 2013
We review recent our results in the fundamental study of surface-enhanced Raman scattering (SERS) with emphasis on experiments that attempted to identify the enhancement and blinking mechanism using single Ag nanoparticle dimers attached to dye molecules. These results are quantitatively discussed in the framework of electromagnetic mechanism.
Yuko S. Yamamoto   +3 more
openaire   +1 more source

Traditional Raman and SERS: Fundamentals and State of the Art

2018
An interesting approach to the study of matter is represented by spectroscopy, that infers information about materials and biosystems by driving their interaction with controlled probes, as beams of light, electrons and neutrons. In this chapter, the basic physics of Raman and Surface Enhanced Raman Scattering (SERS) will be discussed.
openaire   +1 more source

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