Results 101 to 110 of about 1,068,757 (265)

Mendelian Randomization Study With Clinical Follow‐Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Pulmonary arterial hypertension (PAH) exhibits phenotypic heterogeneity and variable response to therapy. The metabolome has been implicated in the pathogenesis of PAH, but previous works have lacked power to implicate specific metabolites ...
Elham Alhathli, Thomas Julian, Zain Ul Abideen Girach, A. A. Roger Thompson, Christopher Rhodes, Stefan Gräf, Niamh Errington, Martin R. Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper‐Knock   +10 more
doaj   +1 more source

Mirror symmetry breaking in micelles of N-stearoyl serine enantiomers [PDF]

arXiv, 2019
Abstract: Circular dichroism spectra were recorded for micellar aggregates of N-stearoyl (L or D) serine in H2O or D2O. Micelle formation kinetics differed markedly in H2O, but in D2O the enantiomers showed similar spectral characteristics. The results confirm previous observations (1) that described differences in the thermodynamic properties of ...
arxiv  

Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients [PDF]

, 2013
We previously reported that AR phosphorylation at serine 213 was associated with poor outcome and may contribute to prostate cancer development and progression.
Black, Callewaert, Chen, Claire Adams, Clare Orange, Fu, Gaughan, Gioeli, Gioeli, Gordon, Hsu, Jennifer Willder, Joanne Edwards, Kirkegaard, Lin, Lindsay Bennett, Mahajan, Mark Underwood, Mccall, Mccall, Mellinghoff, Pamela McCall, Ponguta, Rochette-Egly, Shigemura, Tahir Qayyum, Tam, Taneja, Traynor, Van Laar, Wen, Willder, Wong, Zhou, Zong   +34 more
core   +3 more sources

Expression of Formate-Tetrahydrofolate Ligase Did Not Improve Growth but Interferes With Nitrogen and Carbon Metabolism of Synechocystis sp. PCC 6803

Frontiers in Microbiology, 2020
The introduction of alternative CO2-fixing pathways in photoautotrophic organism may improve the efficiency of biological carbon fixation such as minimizing the carbon loss due to photorespiration.
Shanshan Song, Stefan Timm, Steffen N. Lindner, Viktoria Reimann, Wolfgang R. Hess, Martin Hagemann, Eva-Maria Brouwer   +6 more
doaj   +1 more source

Serine Proteases: an Ab Initio Molecular Dynamics Study [PDF]

arXiv, 1999
In serine proteases (SP's), the H-bond between His-57 and Asp-102, and that between Gly-193 and the transition state intermediate play a crucial role for enzymatic function. To shed light on the nature of these interactions, we have carried out ab initio molecular dynamics simulations on complexes representing adducts between the reaction intermediate ...
arxiv  

Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

, 2019
Erratum for: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Bardeesy, N., Boukhali, M., Chen, T., Dyson, N., Gu, H., Haas, W., Hammerman, P., Hayes, D., Hayward, M., Karnik, R., Kottakis, F., Li, Y., Liesa, M., Meissner, A., Nagle, J., Nicolay, B., Roumane, A., Shirihai, O., Wong, K.   +18 more
core   +1 more source

Latent periodicity of serine-threonine and tyrosine protein kinases and another protein families [PDF]

Molekularnuya Biologiya (Russian), vol.39, N3, 2005, 2004
We identified latent periodicity in catalytic domains of approximately 85% of serine/threonine and tyrosine protein kinases. Similar results were obtained for other 22 protein domains. We also designed the method of noise decomposition, which is aimed to distinguish between different periodicity types of the same period length. The method is to be used
arxiv  

Serine metabolism orchestrates macrophage polarization by regulating the IGF1–p38 axis

Cellular & Molecular Immunology, 2022
Xiao Shan, Penghui Hu, Lina Ni, Long Shen, Yanan Zhang, Zemin Ji, Yan Cui, Meihua Guo, Haoan Wang, Liyuan Ran, Kun Yang, Ting Wang, Lei Wang, Bing Chen, Zhi Yao, Yingjie Wu, Qiujing Yu   +16 more
semanticscholar   +1 more source

Profit with Principles: Norwegian Companies´ Commitment to Transparency in Business [PDF]

This master thesis examinates Norwegian companies´ work with human rights due diligence and the Transparency Act. The aim was to research in what degree companies know whether they violate human rights or not in their value chain.
Johannesen, Serine Vinnes
core  

Roles and regulation of membrane-associated serine proteases [PDF]

, 2007
Pericellular proteolytic activity affects many aspects of cellular behaviour, via mechanisms involving processing of the extracellular matrix, growth factors and receptors.
Bass, Rosemary, Ellis, V, Gray, Kelly, Owen, K, Qiu, Deyi   +4 more
core   +1 more source