Results 81 to 90 of about 725,864 (316)
Amperometric Self-Referencing Ceramic Based Microelectrode Arrays for D-Serine Detection
, 2018 D-serine is the major D-amino acid in the mammalian central nervous system. As the dominant co-agonist of the endogenous synaptic NMDA receptor, D-serine plays a role in synaptic plasticity, learning, and memory.
Campos-Beltran, Diana +12 more
core +2 more sources
Synthesis of cyclobutane serine analogues [PDF]
, 2005 (Chemical Equation Presented). In this paper, we describe a thermal [2 + 2] cycloaddition involving 2-acylaminoacrylates as electron-poor acceptor alkenes, a reaction that involves a Michael-Dieckmann-type process.
Peregrina, J.M. [0000-0003-3778-7065] +3 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Fabrication and use of D-serine biosensors for characterising D-serine signalling in rat brain [PDF]
D-serine is a co-agonist at NMDA receptors in the brain but the study of this amino acid is restricted by current techniques. I have designed highly sensitive D-serine biosensors that permit accurate real-time recordings of D-serine in the brain in a ...
Bibi, Shakila
core
Dual targeting of glutamine and serine metabolism in acute myeloid leukemia
Frontiers in OncologyAcute myeloid leukemia (AML) is a heterogeneous hematological malignancy characterized by disrupted blood cell production and function. Recent investigations have highlighted the potential of targeting glutamine metabolism as a promising therapeutic ...
Kanwal M. Hameed +13 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Genetic Profiles Affect the Biological Effects of Serine on Gastric Cancer Cells
Frontiers in Pharmacology, 2020 A high serine content in body fluid was identified in a portion of patients with gastric cancer, but its biological significance was not clear. Here, we investigated the biological effect of serine on gastric cancer cells.
Jun Li +9 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2016 We report here the enantioselective synthesis of Boc-α-methyl-d-cysteine(PMB)-OH and lanthionine building blocks through the regioselective ring opening of key intermediate Boc-α-methyl-d-serine-β ...
Murray Goodman (2652340) +1 more
core +1 more source
Journal of Integrative AgricultureThis study examined the effect of dietary serine (Ser) on egg white quality, ovomucin content of laying hens fed low-gossypol cottonseed meal (LCSM)-based diet and sought to explore the regulatory mechanism underlying the effects.
Jianmin Zhou +7 more
doaj +1 more source