Results 181 to 190 of about 660,366 (297)

Aspartate availability drives differential engagement of the malate-aspartate shuttle. [PDF]

Mol Cell
Brunner JS, Bridgeman AE, Jackson BT, Chakraborty S, Fagoaga-Eugui M, Paras KI, Xie A, Arnold PK, Losner J, Finley LWS.   +9 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region. [PDF]

Life Sci Alliance
Boggio Bozzo S, Dell'Oca M, Vaglietti S, Gurgone A, Cardinale V, Ragazzini G, Alessandrini A, Colnaghi L, Bazan JF, Ghirardi M, Giustetto M, Fiumara F.   +11 more
europepmc   +1 more source

Protease purification and characterization of a serine protease inhibitor from Egyptian varieties of soybean seeds and its efficacy against Spodoptera littoralis [PDF]

, 2015
Ashraf Oukasha Abd El‐latif
openalex   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Gold Nanocluster-Amino Acid Interactions: Assessment of DFTB with Dispersion Corrections. [PDF]

ACS Omega
Morehouse J, McPhee A, Howie E, L Oliveira LF.   +3 more
europepmc   +1 more source

Three new serine-protease autotransporters of Enterobacteriaceae (SPATEs) from extra-intestinal pathogenic Escherichia coli and combined role of SPATEs for cytotoxicity and colonization of the mouse kidney

, 2019
Hajer Habouria, Pravil Pokharel, Ségolène Maris, Amélie Garénaux, Hicham Bessaiah, Sébastien Houle, Frédéric J. Veyrier, Stéphanie Guyomard-Rabenirina, Antoine Talarmin, Charles M. Dozois   +9 more
openalex   +1 more source

An Emerging Role for Serine Protease Inhibitors in T Lymphocyte Immunity and Beyond [PDF]

, 2012
Philip G. Ashton‐Rickardt
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Serine synthesis and transport mediate the synergistic and detoxifying effects of lienal peptides on cisplatin. [PDF]

Front Pharmacol
Ding K, Yu T, Zhang X, Hu K, Mao S, Zhang T, Liu Y, Wang Z, Fan X, Liu W, Zhang D, He L, Xie L, Wang G, Liang Y.   +14 more
europepmc   +1 more source