Results 11 to 20 of about 776,967 (309)
ترشيد أدوار المرأة في فكر الإمام يوسف القرضاوي [PDF]
مجلة كلية الشريعة والدراسات الإسلاميةأهداف البحث: الاهتداء لمنهجية القرضاوي في ترشيد أدوار المرأة المسلمة، والاعتناء بالمفاهيم والأصول الكبرى التي احتكم إليها في بناء موقفه، واستثمار ما توصل إليه في تعميق أداء المسلمة لواجباتها في واقعنا المعاصر.
Serine Louiz
doaj +2 more sources
Identifying sources of D-serine in Caenorhabditis elegans and their impact on behavior [PDF]
, 2021 Free D-serine (D-Ser) is a potent co-agonist of the N-methyl-D-aspartate receptor (NMDAR) in glutamate neurotransmission and regulates NMDAR functions in the nervous system.
Jonathan V., Sweedler +4 more
core +2 more sources
Cells, 2022 Overexpression of α-synuclein with tyrosine mutated to phenylalanine at position 125 leads to a severe phenotype with motor impairment and neuropathology in Drosophila.
Louise Berkhoudt Lassen +7 more
doaj +1 more source
Targeting one-carbon metabolism requires mTOR inhibition: a new therapeutic approach in osteosarcoma
Molecular & Cellular Oncology, 2021 The rate-limiting enzyme of serine biosynthesis, 3-phosphoglycerate dehydrogenase (PHGDH), contributes to rapid growth and proliferation when it is overexpressed in cancer.
Richa Rathore, Brian Van Tine
doaj +1 more source
, 2023 3,3′,5,5′-Tetramethylbenzidine (TMB)-based catalysis-mediated colorimetric analysis for the detection of small molecules has poor specificity. In this study, well-prepared Au@Cu2O core–shell nanocatalysts (NCs) were fabricated that have excellent ...
Wei-Peng Li (703383) +5 more
core +1 more source
Serine-based surfactants as effective antimicrobial agents against multiresistant bacteria
, 2022 The antimicrobial activity of two serine derived gemini cationic surfactants, amide (12Ser)2CON12 and ester (12Ser)2COO12, was tested using sensitive, E. coli ATCC 25922 and S. aureus ATCC 6538, and resistant, E. coli CTX M2, E.
Rui Pereira (187696) +8 more
core +3 more sources
Neurobiology of Disease, 2014 Although tissue plasminogen activator (tPA) is known to promote neuronal remodeling in the CNS, no mechanism of how this plastic function takes place has been reported so far.
Sighild Lemarchant +17 more
doaj +1 more source
Mapping the ACE2 binding site on the SARS-CoV-2 spike protein S1: molecular recognition pattern [PDF]
Proceedings of the Estonian Academy of Sciences, 2020 Coronavirus SARS-CoV-2 enters the host cell via binding with the angiotensin-converting enzyme 2 (ACE2), and here we used computational modelling to study the molecular recognition pattern of this interaction.
Aleksei Kuznetsov, Jaak Järv
doaj +1 more source
Serine-Selective Bioconjugation
Journal of the American Chemical Society, 2020 The first general method for the rapid, chemoselective, and modular functionalization of serine residues in native polypeptides is reported. Using a reagent platform based on P(V) oxidation state, this redox-economic approach can be used to append nearly any kind of cargo onto serine generating a stable, benign, and hydrophilic phosphorothioate linkage.
Vantourout, Julien C +16 more
openaire +7 more sources
Seprase: An overview of an important matrix serine protease [PDF]
, 2008 Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase, which has been shown to have gelatinase activity. Seprase has a dual function in tumour progression.
O\u27Brien, Pamela +3 more
core +2 more sources