Results 21 to 30 of about 776,967 (309)

Cellular Redox Imbalance and Neurochemical Effect in Cognitive-Deficient Old Rats

Behavioral Sciences, 2018
The purpose of the present study is to access the linkage between dysregulation of glutamatergic neurotransmission, oxidative metabolism, and serine signaling in age-related cognitive decline.
Maria Elena González-Fraguela, Lisette Blanco-Lezcano, Caridad Ivette Fernandez-Verdecia, Teresa Serrano Sanchez, Maria de los A. Robinson Agramonte, Lidia Leonor Cardellá Rosales   +5 more
doaj   +1 more source

T-SP1: a novel serine protease-like protein predominantly expressed in testis [PDF]

, 2008
Here, we describe a novel member in the group of membrane-anchored chymotrypsin (S1)-like serine proteases, namely testis serine protease 1 (T-SP1), as it is principally expressed in testis tissue.
Nerlich, Andreas, Profanter, Birgit, Geissler, Claudia, Neth, Peter, Sommerhoff, Christian P., Naegler, Dorit K., Jochum, Marianne   +6 more
core   +1 more source

A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution

eLife, 2019
In eukaryotes, ribosome profiling provides insight into the mechanism of protein synthesis at the codon level. In bacteria, however, the method has been more problematic and no consensus has emerged for how to best prepare profiling samples.
Fuad Mohammad, Rachel Green, Allen R Buskirk   +2 more
doaj   +1 more source

Amino Acid Levels as Potential Biomarker of Elderly Patients with Dementia

Brain Sciences, 2020
Dementia is a clinical syndrome characterized by cognitive impairment, in which there is disturbance of multiple higher cortical functions. The primary risk factor of dementia is old age, and due to significant changes in the worldwide demographic ...
Edyta Socha, Piotr Kośliński, Marcin Koba, Katarzyna Mądra-Gackowska, Kornelia Kędziora-Kornatowska, Marcin Gackowski, Emilia Daghir-Wojtkowiak   +6 more
doaj   +1 more source

The content of non-essential amino acids in the grains of winter and spring varieties of oats (Avena sativa L.) under the conditions of Central Southern Bulgaria [PDF]

Agroznanje, 2013
The purpose of this survey is to study the content of non-essential amino acids in four winter (Dunav 1, Ruse 8, Resor 1, Line M-K) and five spring (Obraztsov chiflik 4, Mina, HiFi, Novosadski golozarnest and Prista 2) cultivars of oats grown in Central ...
Georgieva T., Zorovski P.
doaj   +1 more source

Effects of D-Serine and MK-801 on Neuropathic Pain and Functional Recovery in a Rat Model of Spinal Cord Injury [PDF]

Neurospine, 2022
Objective Neuropathic pain is a common secondary complication of spinal cord injury (SCI). N-methyl-D-aspartate (NMDA) receptor activation is critical for hypersensitivity in neuropathic pain.
Dongwoo Yu, Seul Ah Mun, Sang Woo Kim, Dae-Chul Cho, Chi Heon Kim, Inbo Han, Subum Lee, Sang-Woo Lee, Kyoung-Tae Kim   +8 more
doaj   +1 more source

Serine proteases [PDF]

IUBMB Life, 2009
AbstractOver one third of all known proteolytic enzymes are serine proteases. Among these, the trypsins underwent the most predominant genetic expansion yielding the enzymes responsible for digestion, blood coagulation, fibrinolysis, development, fertilization, apoptosis, and immunity.
openaire   +3 more sources

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins [PDF]

, 2006
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins
Scorilas, Andreas, Malm, Johan,, Courty, Yves, Ulf-Håkan Stenman, Lundwall, Åke,, Yousef, George M, Georgia Sotiropoulou, Lois J. Maltais, Talieri, Maroulio, Olsson, A Yvonne, Yousef, George, Talieri, M., Malm, Johan, Carsten Stephan, Stephan, Carsten, Blaber, M., Liija, H., Malm, J., Fritz, Hans, Blaber, Michael, Clements, Judith A, Lundwall, A., Lilja, Hans, Andreas Scorilas, Scorilas, A., Olsson, A. Yvonne, Hans Fritz, Judith A. Clements, Fritz, H., Lundwall, Åke, Constantina Petraki, Maltais, Lois J, Sotiropoulou, Georgia, Clements, J A, Clements, Judith, Lund University., Vimla Band, A. Yvonne Olsson, Band, Vimla, Maroulio Talieri, Stephan, C., Lilja, Hans,, Yousef, G M, Petraki, Constantina, Sotiropoulou, G., Courty, Y., Eleftherios P. Diamandis, Åke Lundwall, Michael Blaber, Diamandis, Eleftherios P, Hans Lilja, Stenman, Ulf-Hakan, Diamandis, E P, Maltais, L J, Petraki, C., George M. Yousef, Yves Courty, Olsson, A Y, Band, V., Maltais, Lois, Diamandis, Eleftherios, Johan Malm   +61 more
core   +1 more source

Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation [PDF]

, 2012
Leishmania ISPs are ecotin-like natural peptide inhibitors of trypsin-family serine peptidases, enzymes that are absent from the Leishmania genome. This led to the proposal that ISPs inhibit host serine peptidases and we have recently shown that ISP2 ...
Petr Volf, Mottram, Jeremy C, Gareth D. Westrop, Eschenlauer, Sylvain C, Volf, Petr, Amy Goundry, Sylvain C. Eschenlauer, Jeremy C. Mottram, Lima, Ana Paula C A, Lima, Ana Paula C.A., Morrison, Lesley S, Morrison, Lesley S., Lesley S. Morrison, Ana Paula C. A. Lima, Goundry, Amy, Faria, Marilia S, Marilia S. Faria, Graham H. Coombs, Westrop, Gareth D., Coombs, Graham H, Anna Dostalova, Laurence Tetley, Faria, Marilia S., Tetley, Laurence, Dostalova, Anna, Westrop, Gareth D, Mottram, Jeremy C., Eschenlauer, Sylvain C., Coombs, Graham H.   +28 more
core   +1 more source

Serine Resolvases [PDF]

Microbiology Spectrum, 2015
ABSTRACT Serine resolvases are an interesting group of site-specific recombinases that, in their native contexts, resolve large fused replicons into smaller separated ones. Some resolvases are encoded by replicative transposons and resolve the transposition product, in which the donor and recipient molecules are fused, into separate replicons.
openaire   +2 more sources