Results 231 to 240 of about 951,429 (338)

The E3 Ubiquitin Ligase ARIH1 Facilitates Colorectal Cancer Progression by Promoting Oxidative Phosphorylation via the Mitochondrial Translocation of K63‐Linked Ubiquitinated PHB1

Advanced Science, EarlyView.
The RBR E3 ubiquitin ligase ARIH1, which is upregulated in colorectal cancer cells, promotes cell growth and metastasis and correlates with an unfavorable CRC prognosis. Mechanistically, ARIH1 catalyzes K63‐linked ubiquitination of PHB1, enhancing the interaction between PHB1 and Akt.
Ying Tong, Zhenling Wang, Yong Wang, Yang Chen, Hongqiang Zhang, Yunfei Lu, Lei Xu, Hengyang Shen, Changzhi Huang, Min Zhao, Wenjie Li, Shuai Wang, Yu Shao, Zan Fu   +13 more
wiley   +1 more source

Identification and genetic analysis of candidate genes for resistance against <i>Phytophthora sojae</i> in soybean using a genome-wide association study. [PDF]

Front Plant Sci
Park HR, Heo SV, Kang BK, Seo H, Lee E, Park J, Jang YW, Seo JH, Park G, Kim JH, Lee YH, Han WY, Seo MC, Jeung JU.   +13 more
europepmc   +1 more source

INHIBITION OF MICROBIAL GROWTH AND SEPARATION BYd-SERINE, VANCOMYCIN, AND MITOMYCIN C [PDF]

, 1963
Norman N. Durham
openalex   +1 more source

ON THE SYNTHESIS OF SERINE

Journal of Biological Chemistry, 1940
John Wood, Vincent du Vigneaud
openaire   +2 more sources

Identification and Application of a Novel Patulin Degrading Enzyme From Meyerozyma guilliermondii

Advanced Science, EarlyView.
Patulin (PAT), a hazardous mycotoxin, threatens human health. A novel yeast‐derived short‐chain dehydrogenase/reductase effectively degrades PAT into nontoxic ascladiol via catalytic triad activity. The biological detoxification process has no significant effect on the quality of fresh pear juice.
Yu Zhang, Qianhua Zhao, Solairaj Dhanasekaran, Esa Abiso Godana, Yue Zhang, Xue Bai, Qiya Yang, Hongyin Zhang   +7 more
wiley   +1 more source

The role and research progress of serine metabolism in tumor cells. [PDF]

Front Oncol
Lyu H, Bao S, Cai L, Wang M, Liu Y, Sun Y, Hu X.   +6 more
europepmc   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

Early involvement of D-serine in β-amyloid-dependent pathophysiology. [PDF]

Cell Mol Life Sci
Billard JM, Ploux E, Largilliere S, Corvaisier S, Gorisse-Hussonnois L, Radzishevsky I, Wolosker H, Freret T.   +7 more
europepmc   +1 more source

The metabolism of glycyl-l-serine O[35S]-sulphate in the rat [PDF]

, 1964
N. Tudball, Yukinao Noda, K. S. Dodgson
openalex   +1 more source

Proteomics‐Empowered Microfluidic‐SERS Immunoassay for Identifying and Detecting Biomarkers of Micropapillary Lung Adenocarcinoma

Advanced Science, EarlyView.
The presence of a micropapillary (MPP) component is critical for lung adenocarcinoma (LUAD) surgery, yet reliable blood biomarkers remain lacking. This study integrates proteomics for biomarker identification, a nanomixing‐enhanced surface‐enhanced Raman spectroscopy (SERS) platform for sensitive detection, and machine learning for accurate ...
Dechun Zhang, Kaiming Peng, Hui Xu, Yanping Chen, Jing Wang   +4 more
wiley   +1 more source