Results 21 to 30 of about 660,366 (297)

Genetic Profiles Affect the Biological Effects of Serine on Gastric Cancer Cells

Frontiers in Pharmacology, 2020
A high serine content in body fluid was identified in a portion of patients with gastric cancer, but its biological significance was not clear. Here, we investigated the biological effect of serine on gastric cancer cells.
Jun Li, Hongzhang Xue, Zhen Xiang, Shuzheng Song, Ranlin Yan, Jun Ji, Zhenggang Zhu, Chaochun Wei, Chaochun Wei, Yingyan Yu   +9 more
doaj   +1 more source

Serine Supports IL-1β Production in Macrophages Through mTOR Signaling

Frontiers in Immunology, 2020
Intracellular metabolic programs tightly regulate the functions of macrophages, and previous studies have shown that serine mainly shapes the macrophage function via one-carbon metabolism.
Siyuan Chen, Yaoyao Xia, Fang He, Jian Fu, Zhongquan Xin, Baichuan Deng, Liuqin He, Xihong Zhou, Wenkai Ren   +8 more
doaj   +1 more source

Serine Alleviates Dextran Sulfate Sodium-Induced Colitis and Regulates the Gut Microbiota in Mice

Frontiers in Microbiology, 2018
Serine alleviates inflammatory responses and is beneficial for gut health; however, whether it exerts any effects on ulcerative colitis or regulates intestinal microbiota remains unknown.
Haiwen Zhang, Haiwen Zhang, Rui Hua, Rui Hua, Bingxi Zhang, Bingxi Zhang, Xiaomeng Zhang, Xiaomeng Zhang, Hui Yang, Hui Yang, Xihong Zhou   +10 more
doaj   +1 more source

Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine

Frontiers in Oncology, 2022
The impact of asparaginases on plasma asparagine and glutamine is well established. However, the effect of asparaginases, particularly those derived from Erwinia chrysanthemi (also called crisantaspase), on circulating levels of other amino acids is ...
Dominique Bollino, Dominique Bollino, J. Preston Claiborne, J. Preston Claiborne, Kanwal Hameed, Xinrong Ma, Kayla M. Tighe, Brandon Carter-Cooper, Rena G. Lapidus, Rena G. Lapidus, Erin T. Strovel, Ashkan Emadi, Ashkan Emadi, Ashkan Emadi   +13 more
doaj   +1 more source

ترشيد أدوار المرأة في فكر الإمام يوسف القرضاوي

مجلة كلية الشريعة والدراسات الإسلامية
أهداف البحث: الاهتداء لمنهجية القرضاوي في ترشيد أدوار المرأة المسلمة، والاعتناء بالمفاهيم والأصول الكبرى التي احتكم إليها في بناء موقفه، واستثمار ما توصل إليه في تعميق أداء المسلمة لواجباتها في واقعنا المعاصر.
Serine Louiz
doaj   +1 more source

Molecular structure of a 5,10‐methylenetetrahydrofolate dehydrogenase from the silkworm Bombyx mori

FEBS Open Bio, 2019
The enzyme 5,10‐methylenetetrahydrofolate dehydrogenase (MTHFD) is essential for the production of certain amino acids (glycine, serine, and methionine) and nucleic acids (thymidylate and purine).
Mohammad R. Haque, Akifumi Higashiura, Atsushi Nakagawa, Aiko Hirowatari, Shigeki Furuya, Kohji Yamamoto   +5 more
doaj   +1 more source

SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

Frontiers in Oncology, 2022
Recent research has demonstrated the diverse relationship between tumour metabolism and the tumour microenvironment (TME), for example, abnormal serine metabolism.
Weiyu Kong, Weiyu Kong, Zhongyuan Wang, Nuoran Chen, Yiwen Mei, Yang Li, Yulin Yue   +6 more
doaj   +1 more source

The effect of a methyl group on structure and function: Serine vs. threonine glycosylation and phosphorylation

Frontiers in Molecular Biosciences, 2023
A variety of glycan structures cover the surface of all cells and are involved in myriad biological processes, including but not limited to, cell adhesion and communication, protein quality control, signal transduction and metabolism, while also being ...
Joseph J. Barchi, Caitlin N. Strain
doaj   +1 more source

Serine Metabolism Regulates the Replicative Senescence of Human Dental Pulp Cells through Histone Methylation

Current Issues in Molecular Biology
Tissue regeneration therapy based on human dental pulp cells (hDPCs) faces the distinct challenge of cellular senescence during massive expansion in vitro.
Shuhan Zhou, Jingyao Cui, Yu Shi
doaj   +1 more source

Bio-Insecticide of Thymus vulgaris and Ocimum basilicum Extract from Cell Suspensions and Their Inhibitory Effect against Serine, Cysteine, and Metalloproteinases of the Red Palm Weevil (Rhynchophorus ferrugineus)

Insects, 2021
The current study was designed to investigate the insecticide role of volatile constituents produced from cell suspensions of T. vulgaris and O. basilicum against R. ferrugineus. Constituents were extracted from cell suspension after 40 days.
Hossam Moustafa Darrag, Mohammed Refdan Alhajhoj, Hany Ezzat Khalil   +2 more
doaj   +1 more source