Results 21 to 30 of about 1,068,757 (265)

Amino Acid Profile and Biological Properties of Silk Cocoon as Affected by Water and Enzyme Extraction

open access: yesMolecules, 2021
We compared the efficacy for protein extraction of water versus enzymatic extraction. The amino-acid composition, inhibitory activity against enzymes α-amylase and α-glucosidase, and anti-glycation activities of silk protein extract (SPE) were determined.
Chuleeporn Bungthong   +3 more
doaj   +1 more source

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139*

open access: yesJournal of Biological Chemistry, 1998
When mammalian cell cultures or mice are exposed to ionizing radiation in survivable or lethal amounts, novel mass components are found in the histone H2A region of two-dimensional gels.
E. Rogakou   +4 more
semanticscholar   +1 more source

Cellular Redox Imbalance and Neurochemical Effect in Cognitive-Deficient Old Rats

open access: yesBehavioral Sciences, 2018
The purpose of the present study is to access the linkage between dysregulation of glutamatergic neurotransmission, oxidative metabolism, and serine signaling in age-related cognitive decline.
Maria Elena González-Fraguela   +5 more
doaj   +1 more source

Serine restriction alters sphingolipid diversity to constrain tumor growth

open access: yesNature, 2020
Serine, glycine and other nonessential amino acids are critical for tumour progression, and strategies to limit their availability are emerging as potential therapies for cancer 1 – 3 .
Thangaselvam Muthusamy   +11 more
semanticscholar   +1 more source

SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

open access: yesFrontiers in Oncology, 2022
Recent research has demonstrated the diverse relationship between tumour metabolism and the tumour microenvironment (TME), for example, abnormal serine metabolism.
Weiyu Kong   +6 more
doaj   +1 more source

Heterologous Expression of Serine Hydroxymethyltransferase-3 From Rice Confers Tolerance to Salinity Stress in E. coli and Arabidopsis

open access: yesFrontiers in Plant Science, 2019
Among abiotic stresses, salt stress adversely affects growth and development in rice. Contrasting salt tolerant (CSR27), and salt sensitive (MI48) rice varieties provided information on an array of genes that may contribute for salt tolerance of rice ...
Pragya Mishra   +13 more
doaj   +1 more source

The effect of a methyl group on structure and function: Serine vs. threonine glycosylation and phosphorylation

open access: yesFrontiers in Molecular Biosciences, 2023
A variety of glycan structures cover the surface of all cells and are involved in myriad biological processes, including but not limited to, cell adhesion and communication, protein quality control, signal transduction and metabolism, while also being ...
Joseph J. Barchi, Caitlin N. Strain
doaj   +1 more source

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.

open access: yesCancer Discovery, 2020
A hallmark of metastasis is the adaptation of tumor cells to new environments. Metabolic constraints imposed by the serine and glycine-limited brain environment restrict metastatic tumor growth.
B. Ngo   +39 more
semanticscholar   +1 more source

The content of non-essential amino acids in the grains of winter and spring varieties of oats (Avena sativa L.) under the conditions of Central Southern Bulgaria [PDF]

open access: yesAgroznanje, 2013
The purpose of this survey is to study the content of non-essential amino acids in four winter (Dunav 1, Ruse 8, Resor 1, Line M-K) and five spring (Obraztsov chiflik 4, Mina, HiFi, Novosadski golozarnest and Prista 2) cultivars of oats grown in Central ...
Georgieva T., Zorovski P.
doaj   +1 more source

Prevention of γ-Radiation-Induced DNA Damage in Human Lymphocytes Using a Serine-Magnesium Sulfate Mixture

open access: yesSultan Qaboos University Medical Journal, 2017
Objectives: Ionising radiation has deleterious effects on human cells. N-acetylcysteine (NAC) and cysteine, the active metabolite of NAC, are well-known radioprotective agents.
Vahid Changizi   +3 more
doaj   +1 more source

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