Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke [PDF]
, 2008 Cigarette smoke (CS)–induced lung inflammation involves the reduction of histone deacetylase 2 (HDAC2) abundance, which is associated with steroid resistance in patients with chronic obstructive pulmonary disease and in individuals with severe asthma who
Adenuga, David +4 more
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Sum frequency generation spectroscopy of the attachment disc of a spider [PDF]
, 2021 The pyriform silk of the attachment disc of a spider was studied using infrared-visible vibrational sum frequency generation (SFG) spectroscopy. The spider can attach dragline and radial lines to many kinds of substrates in nature (concrete, alloy, metal,
Hien, Khuat Thi Thu +5 more
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The metabolic reprogramming and vulnerability of SF3B1 mutations
Molecular & Cellular Oncology, 2020 Mutations in the splicing factor 3b subunit 1 (SF3B1) gene create a neomorphic protein that disrupts RNA splicing, but the downstream consequences of this missplicing are unclear.
W. Brian Dalton
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Frontiers in Molecular Biosciences, 2023 A variety of glycan structures cover the surface of all cells and are involved in myriad biological processes, including but not limited to, cell adhesion and communication, protein quality control, signal transduction and metabolism, while also being ...
Joseph J. Barchi, Caitlin N. Strain
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Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients [PDF]
, 2013 We previously reported that AR phosphorylation at serine 213 was associated with poor outcome and may contribute to prostate cancer development and progression.
Black +34 more
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Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. [PDF]
, 2018 Background & aimsHeavy alcohol drinking is associated with pancreatitis, whereas moderate intake lowers the risk. Mice fed ethanol long term show no pancreas damage unless adaptive/protective responses mediating proteostasis are disrupted. Pancreatic
Abrol, Ravinder +13 more
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Frontiers in Nutrition, 2023 Phosphatidylethanolamine is the major inner-membrane lipid in the plasma and mitochondrial membranes. It is synthesized in the endoplasmic reticulum from ethanolamine and diacylglycerol (DAG) by the CDP-ethanolamine pathway and from phosphatidylserine by
Michaela St Germain +2 more
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When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment [PDF]
, 2016 Sensing environmental stimuli is critically important for bacteria when faced with the multitude of adversities presented within the host. Responding appropriately to these signals and in turn integrating these responses into the regulatory network of ...
Connolly, James P.R., Roe, Andrew J.
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ترشيد أدوار المرأة في فكر الإمام يوسف القرضاوي
مجلة كلية الشريعة والدراسات الإسلاميةأهداف البحث: الاهتداء لمنهجية القرضاوي في ترشيد أدوار المرأة المسلمة، والاعتناء بالمفاهيم والأصول الكبرى التي احتكم إليها في بناء موقفه، واستثمار ما توصل إليه في تعميق أداء المسلمة لواجباتها في واقعنا المعاصر.
Serine Louiz
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The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
Cells, 2020 In the past, the importance of serine to pathologic or physiologic anomalies was inadequately addressed. Omics research has significantly advanced in the last two decades, and metabolomic data of various tissues has finally brought serine metabolism to ...
Tirthankar Sinha +3 more
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