Results 31 to 40 of about 1,019,815 (341)

Sum frequency generation spectroscopy of the attachment disc of a spider [PDF]

open access: yes, 2021
The pyriform silk of the attachment disc of a spider was studied using infrared-visible vibrational sum frequency generation (SFG) spectroscopy. The spider can attach dragline and radial lines to many kinds of substrates in nature (concrete, alloy, metal,
Hien, Khuat Thi Thu   +5 more
core   +2 more sources

Diversity in the serine recombinases [PDF]

open access: yesMolecular Microbiology, 2002
SummaryMost site‐specific recombinases fall into one of two families, based on evolutionary and mechanistic relatedness. These are the tyrosine recombinases orλintegrase family and the serine recombinases or resolvase/invertase family. The tyrosine recombinases are structurally diverse and functionally versatile and include integrases, resolvases ...
H M Thorpe, Margaret C. M. Smith
openaire   +3 more sources

Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism [PDF]

open access: yes, 2012
Cancer cells must satisfy the metabolic demands of rapid cell growth within a continually changing microenvironment. We demonstrated that the dynamic posttranslational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a key ...
Clark, Peter M.   +8 more
core   +2 more sources

Orchestrating serine resolvases [PDF]

open access: yesBiochemical Society Transactions, 2010
A remarkable feature of the serine resolvases is their regulation: the wild-type enzymes will catalyse intra- but not inter-molecular recombination, can sense the relative orientation of their sites and can exchange strands directionally, despite the fact that there is no net release of chemical bond energy.
Sherwin P. Montaño   +5 more
openaire   +3 more sources

The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS). [PDF]

open access: yes, 2014
The fundamental role of D-serine as a co-agonist at the N-methyl-D-aspartate receptor (NMDAR), mediating both physiological actions of glutamate in long term potentiation and nociception and also pathological effects mediated by excitotoxicty, are well ...
de Belleroche, J, Paul, P
core   +2 more sources

PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and serine 163

open access: yesFEBS Letters, 1996
The 80kDa yristolated lanine‐ich ‐inase ubstrate (MARCKS) in a major in vivo substrate of protein kinase C (PKC). Here we report that MARCKS is a major substrate for the lipid‐activated PKC‐related kinase (PRK1) in cell extracts. Furthermore, PRK1 is shown to phosphorylate MARCKS on the same sites as PKC in vitro.
Dinah Rahman   +5 more
openaire   +2 more sources

The efficacy of prevention for colon cancer based on the microbiota therapy and the antitumor mechanisms with intervention of dietary Lactobacillus

open access: yesMicrobiology Spectrum, 2023
Gut microbiota and their secreted metabolites have an influence on the initiation and progression of colon cancer. Probiotics are extensively perceived as a potential microbiota-modulation strategy to promote the health of the host, while the ...
Fuqiang Xu   +7 more
doaj   +1 more source

Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients [PDF]

open access: yes, 2013
We previously reported that AR phosphorylation at serine 213 was associated with poor outcome and may contribute to prostate cancer development and progression.
Black   +34 more
core   +3 more sources

Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke [PDF]

open access: yes, 2008
Cigarette smoke (CS)–induced lung inflammation involves the reduction of histone deacetylase 2 (HDAC2) abundance, which is associated with steroid resistance in patients with chronic obstructive pulmonary disease and in individuals with severe asthma who
Adenuga, David   +4 more
core   +2 more sources

QUANTUM-CHEMICAL SIMULATION OF THE INTERACTION OF AMINO ACIDS WITH CALCIUM CARBONATE

open access: yesСовременная наука и инновации, 2023
This article presents the results of quantum chemical modeling of the interaction of the CO32-anion with a number of proteinogenic amino acids to identify the most energetically advantageous system and further compare with the results of a laboratory ...
D. M. Remizov   +4 more
doaj   +1 more source

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