Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine
The impact of asparaginases on plasma asparagine and glutamine is well established. However, the effect of asparaginases, particularly those derived from Erwinia chrysanthemi (also called crisantaspase), on circulating levels of other amino acids is ...
Dominique Bollino+13 more
doaj +1 more source
Classification of subbundles on the Fargues-Fontaine curve [PDF]
We completely classify all subbundles of a given vector bundle on the Fargues-Fontaine curve. Our classification is given in terms of a simple and explicit condition on Harder-Narasimhan polygons. Our proof is inspired by the proof of the main theorem in [Hon19], but also involves a number of nontrivial adjustments.
arxiv +1 more source
‘How will it hit us?’ Introducing artificial intelligence (AI) in the Norwegian healthcare services: Three modes of actor mobilisation [PDF]
This thesis explores the introduction of artificial intelligence (AI) in the Norwegian healthcare services. It does so by focusing on the role of expectations and technological promises related to a future with AI in healthcare and how such visions are ...
Kannelønning, Mari Serine
core
Amino Acid Levels as Potential Biomarker of Elderly Patients with Dementia
Dementia is a clinical syndrome characterized by cognitive impairment, in which there is disturbance of multiple higher cortical functions. The primary risk factor of dementia is old age, and due to significant changes in the worldwide demographic ...
Edyta Socha+6 more
doaj +1 more source
Phosphatidylethanolamine is the major inner-membrane lipid in the plasma and mitochondrial membranes. It is synthesized in the endoplasmic reticulum from ethanolamine and diacylglycerol (DAG) by the CDP-ethanolamine pathway and from phosphatidylserine by
Michaela St Germain+2 more
doaj +1 more source
Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells [PDF]
Previous work has shown that some cancer cells are highly dependent on serine/glycine uptake for proliferation. Although serine and glycine can be interconverted and either might be used for nucleotide synthesis and one-carbon metabolism, we show that ...
Labuschagne, Christiaan F.+4 more
core +2 more sources
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]
Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Bieber+36 more
core +1 more source
Extensions of vector bundles on the Fargues-Fontaine curve II [PDF]
Given two arbitrary vector bundles on the Fargues-Fontaine curve, we completely classify all vector bundles which arise as their extensions.
arxiv
The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS). [PDF]
The fundamental role of D-serine as a co-agonist at the N-methyl-D-aspartate receptor (NMDAR), mediating both physiological actions of glutamate in long term potentiation and nociception and also pathological effects mediated by excitotoxicty, are well ...
de Belleroche, J, Paul, P
core +2 more sources
Classification of quotient bundles on the Fargues-Fontaine curve [PDF]
We completely classify all quotient bundles of a given vector bundle on the Fargues-Fontaine curve. As consequences, we have two additional classification results: a complete classification of all vector bundles that are generated by a fixed number of global sections and a nearly complete classification of subbundles of a given vector bundle.
arxiv +1 more source