When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment [PDF]
Sensing environmental stimuli is critically important for bacteria when faced with the multitude of adversities presented within the host. Responding appropriately to these signals and in turn integrating these responses into the regulatory network of ...
Connolly, James P.R., Roe, Andrew J.
core +2 more sources
On nonemptiness of Newton strata in the $B_\mathrm{dR}^+$-Grassmannian for $\mathrm{GSp}_{2n}$ [PDF]
We build upon our previous work to study the Newton stratification on the $B_\mathrm{dR}^+$-Grassmannian for $\mathrm{GSp}_{2n}$. Our main result gives an explicit classification of all nonempty Newton strata associated to a Frobenius-conjugacy class satisfying certain conditions on the Newton polygon.
arxiv
Extracellular serine controls epidermal stem cell fate and tumor initiation
Tissue stem cells are the cell of origin for many malignancies. Metabolites regulate the balance between self-renewal and differentiation, but whether endogenous metabolic pathways or nutrient availability predispose stem cells towards transformation ...
Sanjeethan C. Baksh+9 more
semanticscholar +1 more source
Serine one-carbon catabolism with formate overflow [PDF]
Serine catabolism to glycine and a one-carbon unit has been linked to the anabolic requirements of proliferating mammalian cells. However, genome-scale modeling predicts a catabolic role with one-carbon release as formate. We experimentally prove that in
Athineos, Dimitris+11 more
core +1 more source
In eukaryotes, ribosome profiling provides insight into the mechanism of protein synthesis at the codon level. In bacteria, however, the method has been more problematic and no consensus has emerged for how to best prepare profiling samples.
Fuad Mohammad+2 more
doaj +1 more source
Amino acid frequency and domain features serve well for random forest based classification of thermophilic and mesophilic protein; a case study on serine proteases [PDF]
Thermostability is an important prerequisite for enzymes employed for industrial applications. Several machine learning based models have thus been formulated for protein classification based on this particular trait. These models have employed features derived from sequences, structures or both resulting in a >93% accuracy based on a 10-fold cross ...
arxiv
Characterization of serine proteinase expression in agaricus bisporus and coprinopsis cinerea by using green fluorescent protein and the A. bisporus SPR1 Promoter [PDF]
The Agaricus bisporus serine proteinase 1 (SPR1) appears to be significant in both mycelial nutrition and senescence of the fruiting body.
Andy M. Bailey+13 more
core +4 more sources
The current study was designed to investigate the insecticide role of volatile constituents produced from cell suspensions of T. vulgaris and O. basilicum against R. ferrugineus. Constituents were extracted from cell suspension after 40 days.
Hossam Moustafa Darrag+2 more
doaj +1 more source
Phosphorylation of CENP-A on serine 7 does not control centromere function [PDF]
CENP-A is the histone H3 variant necessary to specify the location of all eukaryotic centromeres via its CENP-A targeting domain and either one of its terminal regions.
Aslanian A.+9 more
core +1 more source
ترشيد أدوار المرأة في فكر الإمام يوسف القرضاوي
أهداف البحث: الاهتداء لمنهجية القرضاوي في ترشيد أدوار المرأة المسلمة، والاعتناء بالمفاهيم والأصول الكبرى التي احتكم إليها في بناء موقفه، واستثمار ما توصل إليه في تعميق أداء المسلمة لواجباتها في واقعنا المعاصر.
Serine Louiz
doaj +1 more source