Results 41 to 50 of about 1,019,815 (341)

When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment [PDF]

open access: yes, 2016
Sensing environmental stimuli is critically important for bacteria when faced with the multitude of adversities presented within the host. Responding appropriately to these signals and in turn integrating these responses into the regulatory network of ...
Connolly, James P.R., Roe, Andrew J.
core   +2 more sources

ترشيد أدوار المرأة في فكر الإمام يوسف القرضاوي

open access: yesمجلة كلية الشريعة والدراسات الإسلامية
أهداف البحث: الاهتداء لمنهجية القرضاوي في ترشيد أدوار المرأة المسلمة، والاعتناء بالمفاهيم والأصول الكبرى التي احتكم إليها في بناء موقفه، واستثمار ما توصل إليه في تعميق أداء المسلمة لواجباتها في واقعنا المعاصر.
Serine Louiz
doaj   +1 more source

The Serine Recombinases

open access: yesMicrobiology Spectrum, 2014
ABSTRACTIn site-specific recombination, two short DNA sequences (‘sites’) are each cut at specific points in both strands, and the cut ends are rejoined to new partners. The enzymes that mediate recognition of the sites and the subsequent cutting and rejoining steps are called recombinases.
openaire   +3 more sources

Genetic Profiles Affect the Biological Effects of Serine on Gastric Cancer Cells

open access: yesFrontiers in Pharmacology, 2020
A high serine content in body fluid was identified in a portion of patients with gastric cancer, but its biological significance was not clear. Here, we investigated the biological effect of serine on gastric cancer cells.
Jun Li   +9 more
doaj   +1 more source

Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway

open access: yesCells, 2019
Tight regulation of signaling from receptor tyrosine kinases is required for normal cellular functions and uncontrolled signaling can lead to cancer. Fibroblast growth factor receptor 2 (FGFR2) is a receptor tyrosine kinase that induces proliferation and
Patrycja Szybowska   +4 more
doaj   +1 more source

Serine Supports IL-1β Production in Macrophages Through mTOR Signaling

open access: yesFrontiers in Immunology, 2020
Intracellular metabolic programs tightly regulate the functions of macrophages, and previous studies have shown that serine mainly shapes the macrophage function via one-carbon metabolism.
Siyuan Chen   +8 more
doaj   +1 more source

Phosphorylation of Calpastatin Negatively Regulates the Activity of Calpain

open access: yesLife, 2023
Tenderness is an important characteristic of meat quality. Calpastatin and calpain play important roles in meat tenderization. However, it is not clear how phosphorylation affects the regulation of calpastatin on μ-calpain and, consequently, meat ...
Yuqiang Bai   +6 more
doaj   +1 more source

Hanks-Type Serine/Threonine Protein Kinases and Phosphatases in Bacteria: Roles in Signaling and Adaptation to Various Environments [PDF]

open access: yes, 2018
Reversible phosphorylation is a key mechanism that regulates many cellular processes in prokaryotes and eukaryotes. In prokaryotes, signal transduction includes two-component signaling systems, which involve a membrane sensor histidine kinase and a ...
Janczarek, Monika   +3 more
core   +1 more source

Effect of dietary serine supplementation on performance, egg quality, serum indices, and ileal mucosal immunity in laying hens fed a low crude protein diet

open access: yesPoultry Science, 2021
: This study was designed to evaluate the effect of dietary Ser on performance, egg quality, serum indices, and ileal mucosal immunity in laying hens fed low crude protein (LCP), essential amino acids (EAA) balanced diets.
Jian-min Zhou   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

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