Extensions of vector bundles on the Fargues-Fontaine curve II [PDF]
Given two arbitrary vector bundles on the Fargues-Fontaine curve, we completely classify all vector bundles which arise as their extensions.
arxiv
Classification of quotient bundles on the Fargues-Fontaine curve [PDF]
We completely classify all quotient bundles of a given vector bundle on the Fargues-Fontaine curve. As consequences, we have two additional classification results: a complete classification of all vector bundles that are generated by a fixed number of global sections and a nearly complete classification of subbundles of a given vector bundle.
arxiv +1 more source
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase. [PDF]
DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase ...
Johnson, Reid C+4 more
core +1 more source
Orchestrating serine resolvases [PDF]
A remarkable feature of the serine resolvases is their regulation: the wild-type enzymes will catalyse intra- but not inter-molecular recombination, can sense the relative orientation of their sites and can exchange strands directionally, despite the fact that there is no net release of chemical bond energy.
Sherwin P. Montaño+5 more
openaire +3 more sources
Navigating uncertainties of introducing artificial intelligence (AI) in healthcare: The role of a Norwegian network of professionals [PDF]
Artificial Intelligence (AI) technologies are expected to solve pressing challenges in healthcare services world- wide. However, the current state of introducing AI is characterised by several issues complicating and delaying their deployments.
Kannelønning, Mari Serine
core +1 more source
PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and serine 163
The 80kDa yristolated lanine‐ich ‐inase ubstrate (MARCKS) in a major in vivo substrate of protein kinase C (PKC). Here we report that MARCKS is a major substrate for the lipid‐activated PKC‐related kinase (PRK1) in cell extracts. Furthermore, PRK1 is shown to phosphorylate MARCKS on the same sites as PKC in vitro.
Dinah Rahman+5 more
openaire +2 more sources
We determined the kinetic isotope effect on the serine hydroxymethyltransferase reaction (SHMT), which provides important C1 metabolites that are essential for the biosynthesis of DNA bases, O-methyl groups of lignin and methane. An isotope effect on the
Gerd Gleixner
doaj +1 more source
The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases [PDF]
The protein SpoIVB plays a key role in signaling in the sigma (K) checkpoint of Bacillus subtilis. This regulatory mechanism coordinates late gene expression during development in this organism and we have recently shown SpoIVB to be a serine peptidase ...
Brannigan, J A, Cutting, S M, Hoa, N T
core +2 more sources
Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells
Aneuploidy disrupts cellular homeostasis. However, the molecular mechanisms underlying the physiological responses and adaptation to aneuploidy are not well understood.
Sunyoung Hwang+10 more
doaj +1 more source
On nonemptiness of Newton strata in the $B_\mathrm{dR}^+$-Grassmannian for $\mathrm{GSp}_{2n}$ [PDF]
We build upon our previous work to study the Newton stratification on the $B_\mathrm{dR}^+$-Grassmannian for $\mathrm{GSp}_{2n}$. Our main result gives an explicit classification of all nonempty Newton strata associated to a Frobenius-conjugacy class satisfying certain conditions on the Newton polygon.
arxiv