Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]
, 2016 Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel +4 more
core +1 more source
A proposed mechanism for IS607-family serine transposases [PDF]
, 2013 Background The transposases encoded by the IS607 family of mobile elements are unusual serine recombinases with an inverted domain order and minimal specificity for target DNA.<p></p> Results Structural genomics groups have determined ...
Boocock, M.R., Rice, P.A.
core +1 more source
The serine transporter SdaC prevents cell lysis upon glucose depletion in Escherichia coli
MicrobiologyOpen, 2020 The amino acid serine plays diverse metabolic roles, yet bacteria actively degrade exogenously provided serine via deamination to pyruvate. Serine deamination is thought to be a detoxification mechanism due to the ability of serine to inhibit several ...
Michelle A. Kriner +1 more
doaj +1 more source
On certain extensions of vector bundles in p-adic geometry [PDF]
arXiv, 2020 Given two arbitrary vector bundles on the Fargues-Fontaine curve, we give an explicit criterion in terms of Harder-Narasimhan polygons on whether they realize a semistable vector bundle as their extensions. Our argument is largely combinatorial and builds upon the dimension analysis of certain moduli spaces of bundle maps developed in [BFH+22].
arxiv
The Relationship Between Cognitive Distortions and ADHD After Accounting for Depression, Anxiety, and Personality Pathology [PDF]
, 2016 Adults with attention-deficit/hyperactivity disorder (ADHD) suffer from numerous difficulties in daily functioning and, unfortunately, the medications that are typically the first-line of treatment do not ameliorate many of these issues.
Serine, Amelia
core +1 more source
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase. [PDF]
, 2016 DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase ...
Johnson, Reid C +4 more
core +1 more source
The host metabolite D-serine contributes to bacterial niche specificity through gene selection [PDF]
, 2014 Escherichia coli comprise a diverse array of both commensals and niche-specific pathotypes. The ability to cause disease results from both carriage of specific virulence factors and regulatory control of these via environmental stimuli.
A Holmes +68 more
core +2 more sources
Integrating computer software within the Houghton Mifflin Language Arts program [PDF]
, 2005 This project was created for third grade teachers who use the Houghton Mifflin Language Arts series and want to integrate computer software into their writing curriculum.
Ouren, Leslie Serine
core +1 more source
cGMP-dependent protein kinase regulates Rap1 signaling in platelets : poster presentation [PDF]
, 2007 cGMP- and cAMP-dependent protein kinases (cGK and cAK) mediate the inhibitory effects of endothelium-derived messenger molecules nitric oxide and prostacyclin on platelets.
Danielewski, Oliver +5 more
core +1 more source
The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
Cells, 2020 In the past, the importance of serine to pathologic or physiologic anomalies was inadequately addressed. Omics research has significantly advanced in the last two decades, and metabolomic data of various tissues has finally brought serine metabolism to ...
Tirthankar Sinha +3 more
doaj +1 more source