Modeling and structural analysis of PA clan serine proteases
BMC Research Notes, 2012 Background Serine proteases account for over a third of all known proteolytic enzymes; they are involved in a variety of physiological processes and are classified into clans sharing structural homology. The PA clan of endopeptidases is the most abundant
Laskar Aparna +3 more
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T-SP1: a novel serine protease-like protein predominantly expressed in testis [PDF]
, 2008 Here, we describe a novel member in the group of membrane-anchored chymotrypsin (S1)-like serine proteases, namely testis serine protease 1 (T-SP1), as it is principally expressed in testis tissue.
Nerlich, Andreas +6 more
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Sensitive substrates for neprilysin (neutral endopeptidase) and thermolysin that are highly resistant to serine proteases [PDF]
FEBS Letters, 1996 Tripeptide derivatives like 3‐carboxypropanoylalanyl‐alanyl‐leucine 4‐nitroanilide or 3‐carboxypropanoylalanyl‐alanyl‐phenylalanine 4‐nitroanilide are very sensitive substrates for neprilysin (k cat > 102 s−1; k cat/K m ≥ 106 s−1 · M−1) and are widely employed in investigations of the enzyme. However, these compounds are also good substrates for the
Spungin-Bialik, Anya +4 more
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MEPE-derived ASARM peptide inhibits odontogenic differentiation of dental pulp stem cells and impairs mineralization in tooth models of X-linked hypophosphatemia. [PDF]
PLoS ONE, 2013 Mutations in PHEX (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) cause X-linked familial hypophosphatemic rickets (XLH), a disorder having severe bone and tooth dentin mineralization defects.
Benjamin Salmon +17 more
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Genetic divergence between populations of feral and domestic forms of a mosquito disease vector assessed by transcriptomics [PDF]
PeerJ, 2015 Culex pipiens, an invasive mosquito and vector of West Nile virus in the US, has two morphologically indistinguishable forms that differ dramatically in behavior and physiology. Cx.
Dana C. Price, Dina M. Fonseca
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BMC Evolutionary Biology, 2011 Background Omptins are a family of outer membrane proteases that have spread by horizontal gene transfer in Gram-negative bacteria that infect vertebrates or plants.
Westerlund-Wikström Benita +3 more
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Oral Interview of Serine Bale [PDF]
, 1975 Serine Bale talks about her family’s pioneer history and her experiences in rural schools. She also discusses how different events in American history were perceived at the time and affected life in rural North Dakota.https://red.mnstate.edu ...
Bale, Serine
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Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Angewandte Chemie, EarlyView.Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Using the SUBcellular database for Arabidopsis proteins to localize the Deg protease family
Frontiers in Plant Science, 2014 Sub-functionalization during the expansion of gene families in eukaryotes has occurred in part through specific subcellular localization of different family members.
Sandra Karin Tanz +7 more
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Biotechnology for Biofuels and Bioproducts, 2023 Background Keratin, the main component of chicken feather, is the third most abundant material after cellulose and chitin. Keratin can be converted into high-value compounds and is considered a potential high-quality protein supplement; However, its ...
Yuhong Lai +4 more
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