Results 11 to 20 of about 122,475 (202)

Serine-based surfactants as effective antimicrobial agents against multiresistant bacteria

, 2022
The antimicrobial activity of two serine derived gemini cationic surfactants, amide (12Ser)2CON12 and ester (12Ser)2COO12, was tested using sensitive, E. coli ATCC 25922 and S. aureus ATCC 6538, and resistant, E. coli CTX M2, E.
Rui Pereira (187696), Salette Reis (1539037), Sandra G. Silva (1647406), Cristina Prudêncio (17751891), M. Luísa C. do Vale (17751894), Peter Eaton (17171803), Marina Pinheiro (8463060), Ricardo Ferraz (2490775), Ana Rita Dias (16561128)   +8 more
core   +5 more sources

Cell Wall Endopeptidases in Pseudomonas Aeruginosa

, 2020
The bacterial cell wall is essential for viability, and thus represents an attractive target for antibiotic therapy. Although beta-lactams and certain other antibiotics target enzymes involved in cell wall synthesis, pathogens are rapidly becoming ...
Tom, Michael R.
core   +4 more sources

Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]

, 2003
Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Eggen, BJL, Vellenga, E, Vellenga, Edo,, Vogelzang, Irma, Eggen, BJL; id_orcid, Vogelzang, Irma,, Wierenga, Albertus T.J., Wierenga, Albertus T.J.,, Eggen, Bart J.L.,   +8 more
core   +1 more source

Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis

Parasites & Vectors, 2018
Background The salmon louse, Lepeophtheirus salmonis, is an ectoparasitic copepod which feeds on the mucus, skin and blood of salmonid fish species. The parasite can persist on the surface of the fish without any effective control being exerted by the ...
Scott Hamilton, Kevin McLean, Sean J. Monaghan, Carol McNair, Neil F. Inglis, Hazel McDonald, Sandra Adams, Randolph Richards, William Roy, Patrick Smith, James Bron, Alasdair J. Nisbet, David Knox   +12 more
doaj   +1 more source

Plant-Programmed Cell Death-Associated Genes Participation in Pinus sylvestris L. Trunk Tissue Formation

Plants, 2022
Molecular genetic markers of various PCD (programmed cell death) variants during xylo- and phloemogenesis have been identified for the first time in Scots pine under lingonberry pine forest conditions in Northwest Russia (middle taiga subzone).
Yulia L. Moshchenskaya, Natalia A. Galibina, Kseniya M. Nikerova, Tatiana V. Tarelkina, Maksim A. Korzhenevsky, Irina N. Sofronova, Maria A. Ershova, Ludmila I. Semenova   +7 more
doaj   +1 more source

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Molecules, 2018
The synthesis of racemic substituted 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one hydrochlorides was optimized to enhance reproducibility and increase the overall yield.
Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Céline Schmitt, Sarah Alavi, Isabelle Florent, Anthony Addlagatta, Efstratios Stratikos, Céline Tarnus, Sébastien Albrecht   +11 more
doaj   +1 more source

Alterations in gene expression of proprotein convertases in human lung cancer have a limited number of scenarios. [PDF]

PLoS ONE, 2013
Proprotein convertases (PCs) is a protein family which includes nine highly specific subtilisin-like serine endopeptidases in mammals. The system of PCs is involved in carcinogenesis and levels of PC mRNAs alter in cancer, which suggests expression ...
Ilya V Demidyuk, Andrey V Shubin, Eugene V Gasanov, Alexander M Kurinov, Vladimir V Demkin, Tatyana V Vinogradova, Marina V Zinovyeva, Alexander V Sass, Irina B Zborovskaya, Sergey V Kostrov   +9 more
doaj   +1 more source

The midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape

BMC Genomics, 2017
Background The mosquito Aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (CHIKV). Following oral acquisition, an arbovirus has to persistently infect several organs in the mosquito before ...
Shengzhang Dong, Susanta K. Behura, Alexander W. E. Franz   +2 more
doaj   +1 more source

Homologous inhibitors from potato tubers of serine endopeptidases and metallocarboxypeptidases. [PDF]

Proceedings of the National Academy of Sciences, 1976
A potent polypeptide inhibitor of chymotrypsin has been purified from Russett Burbank potatoes. The inhibitor has no effect on bovine carboxypeptidases A or B but exhibits homology with a carboxypeptidase inhibitor that is also present in potato tubers.
C M, Hass, R, Venkatakrishnan, C A, Ryan
openaire   +2 more sources

Seprase: An overview of an important matrix serine protease [PDF]

, 2008
Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase, which has been shown to have gelatinase activity. Seprase has a dual function in tumour progression.
O\u27Brien, Pamela, O'Brien, Pamela, O'Connor, Brendan, O\u27Connor, Brendan   +3 more
core   +2 more sources