Results 131 to 140 of about 6,315 (155)

Integrating recombinase-based feedback and feedforward control for optimal resource decoupling. [PDF]

Nucleic Acids Res
Zhang R, Zhang R, Tian XJ.
europepmc   +1 more source

Characterization of a novel composite ICE in <i>Streptococcus agalactiae</i> conferring resistance to macrolides [<i>erm</i>(TR)] and cadmium (<i>cadA</i>). [PDF]

Front Microbiol
Yi S, Shi C, Yin L, Xu X, Wang X.
europepmc   +1 more source

Balancing complexity and clarity-towards clinician-ready antibiotic resistance prediction models. [PDF]

Bioinformatics
Aruhomukama D.
europepmc   +1 more source

Genomic and experimental characterization of unique Antarctic temperate phage Perkons reveals multiple integrases and complex lysogenic dynamics in Psychrobacillus sp. L4. [PDF]

BMC Microbiol
Zrelovs N, Svanberga K, Priedeslaipa A, Jansons J, Lamsters K, Karuss J, Krievans M, Fridmanis D, Dislers A, Kazaks A.   +9 more
europepmc   +1 more source

The fitness connection of antibiotic resistance. [PDF]

Front Microbiol
Fuzi M.
europepmc   +1 more source

Macrolide resistance determinants and their associations in streptococci from selected livestock and wildlife species from Catalonia, Northeast Spain. [PDF]

Microbiol Spectr
López de Egea G, González-Díaz A, Aragón V, Cabezón O, Guédon G, Berbel D, Cadenas-Jiménez I, Espunyes J, Planellas M, Domínguez MÁ, Leblond-Bourget N, Ardanuy C.   +11 more
europepmc   +1 more source

Tetrameric Structure of a Serine Integrase Catalytic Domain [PDF]

Structure, 2008
The serine integrases have recently emerged as powerful new chromosome engineering tools in various organisms and show promise for therapeutic use in human cells. The serine integrases are structurally and mechanistically unrelated to the bacteriophage lambda integrase but share a similar catalytic domain with the resolvase/invertase enzymes typified ...
Peng Yuan, Kushol Gupta, Gregory D Van Duyne   +2 more
exaly   +4 more sources

Integration and excision by the large serine recombinase φRv1 integrase [PDF]

Molecular Microbiology, 2005
SummaryThe Mycobacterium tuberculosis prophage‐like element φRv1 encodes a site‐specific recombination system utilizing an integrase of the serine recombinase family. Recombination occurs between a putative attP site and the host chromosome, but is unusual in that the attB site lies within a redundant repetitive element (REP13E12)  of  which  there ...
Graham F․ Hatfull
exaly   +4 more sources

Rapid Optimization of Engineered Metabolic Pathways with Serine Integrase Recombinational Assembly (SIRA)

Methods in Enzymology, 2016
Metabolic pathway engineering in microbial hosts for heterologous biosynthesis of commodity compounds and fine chemicals offers a cheaper, greener, and more reliable method of production than does chemical synthesis. However, engineering metabolic pathways within a microbe is a complicated process: levels of gene expression, protein stability, enzyme ...
S D Colloms
exaly   +4 more sources