Results 231 to 240 of about 245,013 (288)
Biocatalytic Regioselective C‐Formylation of Resorcinol Derivatives
Angewandte Chemie, EarlyView.An acyltransferase from Chromobacterium sphagni (CsATase) was identified that catalyzes the regioselective formylation of resorcinol substrates. The formylation of substituted resorcinol derivatives yielded mono‐formylated products with up to 99% conversion and up to 74% isolated yield.
Lilla Gal +6 more
wiley +1 more source
Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
Angewandte Chemie, EarlyView.This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
wiley +1 more source
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Serine metabolism in macrophage polarization
Inflammation Research, 2023Emerging studies have revealed that macrophages possess different dependences on the uptake, synthesis, and metabolism of serine for their activation and functionalization, necessitating our insight into how serine availability and utilization impact macrophage activation and inflammatory responses.This article summarizes the reports published ...
Xinqiong, Huang +3 more
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Serine metabolism and psychosis
Psychiatry Research, 1984Plasma serine levels (PSL) in a group of patients with the diagnosis of major or atypical psychoses were significantly higher than in patients with nonpsychotic diagnoses or nonpatient controls. The enzyme serine hydroxymethyltransferase (SHMT), which metabolizes serine to glycine, showed abnormal activity in the psychotics compared to nonpsychotics ...
R, Waziri +3 more
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Serine signaling governs metabolic homeostasis and health
Trends in Endocrinology & Metabolism, 2023Serine has functions that are involved in metabolic homeostasis and health in pathological or stressful situations. Notably, the de novo serine synthesis pathway (SSP) plays a vital role in targeted regulation of immune responses, cell proliferation, and lipid/protein metabolism.
Liuqin He +4 more
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Metabolic control analysis of mammalian serine metabolism
Advances in Enzyme Regulation, 1990(1) Mammalian serine metabolism is discussed in relation to its synthesis and utilization in proliferating cells, particularly during the nonmalignant proliferation of lymphocytes. (2) An analysis of the control of serine biosynthesis de novo under conditions of high pathway flux has been carried out using metabolic control theory.
K, Snell, D A, Fell
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Serine Metabolism After Portacaval Shunt
Archives of Surgery, 1970Although portacaval shunt effectively controls hemorrhage from esophageal varices by control of portal hypertension, liver function does not improve and often deteriorates after diversion of portal blood from the liver. Hepatic failure is the most common cause of the excessively high mortality following portacaval shunt. The etiology of hepatic failure
F A, Reichle +5 more
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Serine metabolism in Lactobacillus plantarum
International Journal of Food Microbiology, 2003This study investigated the metabolism of (L-) serine by Lactobacillus plantarum B3089 isolated from cheese. Serine was deaminated by growing cells to ammonia with the corresponding formation of acetate and formate. Serine was also deaminated by non-growing cells to ammonia but with the formation of acetate only (no production of formate ...
S-Q, Liu +3 more
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