Results 211 to 220 of about 256,312 (241)
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The metabolism of serine in pyridoxine deficiency
Proceedings / Indian Academy of Sciences, 1957Deficiency of vitamin B6 in rats had no effect on serine decarboxylation, though, serine deamination and glycine to serine synthesis were reduced.
G. B. Nadkarni, A. Sreenivasan
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Regulatory phenomena in mammalian serine metabolism
Advances in Enzyme Regulation, 1967Abstract The biosynthesis of serine in mammalian liver may proceed by two parallel pathways. Serine in physiological concentrations inhibits P-serine phosphatase, the last reaction in the “phosphorylated pathway”. No amino acid inhibitors of the alternative pathway have been identified.
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The metabolism of serine in biotin deficiency
Proceedings / Indian Academy of Sciences, 1957Synthesis of serine from ethanolamine by carbon dioxide fixation is demonstrated to take place in presence of rat liver enzymes. The system is biotin-dependent.
G. B. Nadkarni, A. Sreenivasan
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Comparative Biochemistry and Physiology Part A: Physiology, 1971
Abstract 1. 1. The incorporation of 14C from uniformly labeled, 1-14C labeled and 3-14C labeled serine into various metabolic fractions in Trypanosoma cruzi has been studied. 2. 2. 14C from serine is incorporated into all major metabolic fractions, except the nucleic acid-containing fraction. 3. 3. The results suggest that T. cruzi is not
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Abstract 1. 1. The incorporation of 14C from uniformly labeled, 1-14C labeled and 3-14C labeled serine into various metabolic fractions in Trypanosoma cruzi has been studied. 2. 2. 14C from serine is incorporated into all major metabolic fractions, except the nucleic acid-containing fraction. 3. 3. The results suggest that T. cruzi is not
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Anaerobic Glucose and Serine Metabolism in Staphylococcus epidermidis
Microbiology, 1980Anaerobically grown Staphylococcus epidermidis fermented glucose with the production of lactate and trace amounts of acetate, formate and CO2. Isotopic and inhibitor studies, assays for key enzymes of different metabolic pathways, and fermentation balances, all indicated that glucose was metabolized principally via glycolysis and to a very limited ...
R, Sivakanesan, E A, Dawes
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Abnormal serine-glycine metabolism in the brains of schizophrenics
Schizophrenia Research, 1993The metabolism of serine and glycine as studied in the plasma is abnormal in schizophrenics and psychotics. There is a concomitant abnormality of the enzyme serine hydroxymethyl transferase (SHMT). To study the status of serine-glycine metabolism in brains of schizophrenics and controls, frozen autopsied brain tissues were obtained from medial and ...
R, Waziri, S, Baruah, A D, Sherman
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Serine metabolism in rat embryos undergoing organogenesis
Development, 1985ABSTRACT Rat embryos (9·5 days gestation) were cultured for 48 h in heat-inactivated homologous serum containing [3-14C] serine. Analysis of the distribution of the radioactive label in the conceptus demonstrated that almost one half of the incorporated serine was cleaved to provide one-carbon units for the synthesis of purine and ...
P B, Rowe, A, Kalaizis
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A comprehensive review on signaling attributes of serine and serine metabolism in health and disease
International Journal of Biological MacromoleculesSerine is a metabolite with ever-expanding metabolic and non-metabolic signaling attributes. By providing one‑carbon units for macromolecule biosynthesis and functional modifications, serine and serine metabolism largely impinge on cellular survival and function.
Di, Wu +6 more
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Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2003The first step in the biosynthesis of sphingolipids is the condensation of serine and palmitoyl CoA, a reaction catalyzed by serine palmitoyltransferase (SPT) to produce 3-ketodihydrosphingosine (KDS). This review focuses on recent advances in the biochemistry and molecular biology of SPT.
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Disorders of Proline and Serine Metabolism
2000Four disorders of proline metabolism are known: two in its catabolism (hyperprolinaemia type I, which is due to proline oxidase deficiency, and hyperprolinaemia type II, which is due to ∆-pyrroline 5-carboxylate dehydrogenase deficiency) and two in its synthesis (∆1-pyrroline 5-carboxylate synthase deficiency and ∆-pyrroline 5-carboxylate reductase ...
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