Results 201 to 210 of about 256,312 (241)
Some of the next articles are maybe not open access.
Metabolism of the neuromodulator d-serine
Cellular and Molecular Life Sciences, 2010Over the past years, accumulating evidence has indicated that D-serine is the endogenous ligand for the glycine-modulatory binding site on the NR1 subunit of N-methyl-D-aspartate receptors in various brain areas. D-Serine is synthesized in glial cells and neurons by the pyridoxal-5' phosphate-dependent enzyme serine racemase, and it is released upon ...
POLLEGIONI, LOREDANO, SACCHI, SILVIA
openaire +3 more sources
Serine metabolism in Lactobacillus plantarum
International Journal of Food Microbiology, 2003This study investigated the metabolism of (L-) serine by Lactobacillus plantarum B3089 isolated from cheese. Serine was deaminated by growing cells to ammonia with the corresponding formation of acetate and formate. Serine was also deaminated by non-growing cells to ammonia but with the formation of acetate only (no production of formate ...
S-Q, Liu +3 more
openaire +2 more sources
Metabolic control analysis of mammalian serine metabolism
Advances in Enzyme Regulation, 1990(1) Mammalian serine metabolism is discussed in relation to its synthesis and utilization in proliferating cells, particularly during the nonmalignant proliferation of lymphocytes. (2) An analysis of the control of serine biosynthesis de novo under conditions of high pathway flux has been carried out using metabolic control theory.
K, Snell, D A, Fell
openaire +2 more sources
Serine and glycine metabolism in schizophrenic patients
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 19921. The brain glycine is almost exclusively derived from serine via serine-hydroxymethyltransferase. 17 males schizophrenic inpatients and 10 males healthy volunteers were submitted to the serine tolerance test. 2. Plasma serine and glycine concentration were evaluated before and after 1, 2, 3, 4 hours of an oral load with L-serine to test the ...
A, Lucca, S, Cortinovis, V, Lucini
openaire +2 more sources
Neuroleptic effects on serine and glycine metabolism
Biological Psychiatry, 1993The concentrations of serine and glycine and the activity of serine hydroxymethyltransferase (SHMT) are abnormal in plasma and brains of schizophrenics. To further elucidate the possible role of neuroleptics on the metabolism of serine and glycine and the activity of SHMT, we studied the plasma of controls and schizophrenics on and off medications, the
S, Baruah, R, Waziri, A, Sherman
openaire +2 more sources
Serine Metabolism After Portacaval Shunt
Archives of Surgery, 1970Although portacaval shunt effectively controls hemorrhage from esophageal varices by control of portal hypertension, liver function does not improve and often deteriorates after diversion of portal blood from the liver. Hepatic failure is the most common cause of the excessively high mortality following portacaval shunt. The etiology of hepatic failure
F A, Reichle +5 more
openaire +2 more sources
Serine signaling governs metabolic homeostasis and health
Trends in Endocrinology & Metabolism, 2023Serine has functions that are involved in metabolic homeostasis and health in pathological or stressful situations. Notably, the de novo serine synthesis pathway (SSP) plays a vital role in targeted regulation of immune responses, cell proliferation, and lipid/protein metabolism.
Liuqin He +4 more
openaire +2 more sources
Metabolism of serine and glycine in baker's yeast
Biochimica et Biophysica Acta (BBA) - General Subjects, 1967Abstract 1. 1. Synthesis of serine in baker's yeast takes place by condensation of glycine with a one-carbon unit derived from formate. The reaction is reversible, as shown by the incorporation of radioactivity from [3-14C]serine into adenine, guanine and histidine. 2. 2.
J F, De Boiso, A O, Stoppani
openaire +2 more sources
Serine in plants: biosynthesis, metabolism, and functions
Trends in Plant Science, 2014Serine (Ser) has a fundamental role in metabolism and signaling in living organisms. In plants, the existence of different pathways of Ser biosynthesis has complicated our understanding of this amino acid homeostasis. The photorespiratory glycolate pathway has been considered to be of major importance, whereas the nonphotorespiratory phosphorylated ...
Roc, Ros +2 more
openaire +2 more sources
Serine Palmitoyltransferase Subunit 3 and Metabolic Diseases
2022Sphingolipids (SL) are a class of chemically diverse lipids that have important structural and physiological functions in eukaryotic cells. SL entail a long chain base (LCB) as the common structural element, which is typically formed by the condensation of L-serine and long chain acyl-CoA.
Lone, Museer A +2 more
openaire +2 more sources