Results 231 to 240 of about 1,285,254 (263)
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Serine signaling governs metabolic homeostasis and health
Trends in Endocrinology & Metabolism, 2023Serine has functions that are involved in metabolic homeostasis and health in pathological or stressful situations. Notably, the de novo serine synthesis pathway (SSP) plays a vital role in targeted regulation of immune responses, cell proliferation, and lipid/protein metabolism.
Liuqin He +4 more
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Metabolism of serine and glycine in baker's yeast
Biochimica et Biophysica Acta (BBA) - General Subjects, 1967Abstract 1. 1. Synthesis of serine in baker's yeast takes place by condensation of glycine with a one-carbon unit derived from formate. The reaction is reversible, as shown by the incorporation of radioactivity from [3-14C]serine into adenine, guanine and histidine. 2. 2.
J F, De Boiso, A O, Stoppani
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Serine in plants: biosynthesis, metabolism, and functions
Trends in Plant Science, 2014Serine (Ser) has a fundamental role in metabolism and signaling in living organisms. In plants, the existence of different pathways of Ser biosynthesis has complicated our understanding of this amino acid homeostasis. The photorespiratory glycolate pathway has been considered to be of major importance, whereas the nonphotorespiratory phosphorylated ...
Roc, Ros +2 more
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The metabolism of serine in pyridoxine deficiency
Proceedings / Indian Academy of Sciences, 1957Deficiency of vitamin B6 in rats had no effect on serine decarboxylation, though, serine deamination and glycine to serine synthesis were reduced.
G. B. Nadkarni, A. Sreenivasan
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Serine Palmitoyltransferase Subunit 3 and Metabolic Diseases
2022Sphingolipids (SL) are a class of chemically diverse lipids that have important structural and physiological functions in eukaryotic cells. SL entail a long chain base (LCB) as the common structural element, which is typically formed by the condensation of L-serine and long chain acyl-CoA.
Lone, Museer A +2 more
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Regulatory phenomena in mammalian serine metabolism
Advances in Enzyme Regulation, 1967Abstract The biosynthesis of serine in mammalian liver may proceed by two parallel pathways. Serine in physiological concentrations inhibits P-serine phosphatase, the last reaction in the “phosphorylated pathway”. No amino acid inhibitors of the alternative pathway have been identified.
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The metabolism of serine in biotin deficiency
Proceedings / Indian Academy of Sciences, 1957Synthesis of serine from ethanolamine by carbon dioxide fixation is demonstrated to take place in presence of rat liver enzymes. The system is biotin-dependent.
G. B. Nadkarni, A. Sreenivasan
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Comparative Biochemistry and Physiology Part A: Physiology, 1971
Abstract 1. 1. The incorporation of 14C from uniformly labeled, 1-14C labeled and 3-14C labeled serine into various metabolic fractions in Trypanosoma cruzi has been studied. 2. 2. 14C from serine is incorporated into all major metabolic fractions, except the nucleic acid-containing fraction. 3. 3. The results suggest that T. cruzi is not
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Abstract 1. 1. The incorporation of 14C from uniformly labeled, 1-14C labeled and 3-14C labeled serine into various metabolic fractions in Trypanosoma cruzi has been studied. 2. 2. 14C from serine is incorporated into all major metabolic fractions, except the nucleic acid-containing fraction. 3. 3. The results suggest that T. cruzi is not
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Anaerobic Glucose and Serine Metabolism in Staphylococcus epidermidis
Microbiology, 1980Anaerobically grown Staphylococcus epidermidis fermented glucose with the production of lactate and trace amounts of acetate, formate and CO2. Isotopic and inhibitor studies, assays for key enzymes of different metabolic pathways, and fermentation balances, all indicated that glucose was metabolized principally via glycolysis and to a very limited ...
R, Sivakanesan, E A, Dawes
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Serine metabolism in rat embryos undergoing organogenesis
Development, 1985ABSTRACT Rat embryos (9·5 days gestation) were cultured for 48 h in heat-inactivated homologous serum containing [3-14C] serine. Analysis of the distribution of the radioactive label in the conceptus demonstrated that almost one half of the incorporated serine was cleaved to provide one-carbon units for the synthesis of purine and ...
P B, Rowe, A, Kalaizis
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