Results 11 to 20 of about 265,042 (263)
Frontiers in Pharmacology, 2022 Background: Serine proteases are believed to play a key role in the origin of abdominal pain in IBD and IBS. We previously demonstrated a reduction of visceral pain in a post-inflammatory IBS rat model after a single intraperitoneal or intracolonic ...
Hannah Ceuleers +26 more
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Preliminary investigations on the serine and aspartic protease inhibitors from Nothopegia beddomei
Ceylon Journal of Science, 2019 Aqueous stem bark extract of Nothopegia beddomei was assayed for serine and aspartic protease inhibitors by using trypsin and pepsin as the target enzymes, respectively. Crude bark extract was dialyzed and subjected to inhibition assays.
M.G.K.P. Dayarathne, Sanath Rajapakse
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IUBMB Life, 2009 AbstractOver one third of all known proteolytic enzymes are serine proteases. Among these, the trypsins underwent the most predominant genetic expansion yielding the enzymes responsible for digestion, blood coagulation, fibrinolysis, development, fertilization, apoptosis, and immunity.
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Serine proteases, their inhibitors and allergy [PDF]
Allergy, 2006 This paper reviews four serine protease inhibitors and three protease gene defects that are associated with allergic conditions, suggesting an important role for these genes and their products in the development of allergy. Serine protease inhibitors may have a therapeutic potential in the treatment of allergy.
Smith, P K, Harper, J I
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Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease. [PDF]
PLoS ONE, 2014 Fusobacterium nucleatum is an oral anaerobe associated with periodontal disease, adverse pregnancy outcomes and colorectal carcinoma. A serine endopeptidase of 61-65 kDa capable of damaging host tissue and of inactivating immune effectors was detected ...
Lior Doron +6 more
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Molecules, 2011 Response surface methodology (RSM) using a central composite design (CCD) was employed to optimize the conditions for extraction of serine protease from kesinai (Streblus asper) leaves.
Md. Zaidul Islam Sarker +3 more
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In vitro characterization of jellyfish venom fibrin(ogen)olytic enzymes from Nemopilema nomurai
Journal of Venomous Animals and Toxins including Tropical Diseases, 2017 Background Because jellyfish are capable of provoking envenomation in humans, they are considered hazardous organisms. Although the effects of their toxins are a matter of concern, information on the venom components, biological activity and pathological
Seong Kyeong Bae +8 more
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BMC Evolutionary Biology, 2018 Background The ascomycete fungus Clonostachys rosea (order Hypocreales) can control several important plant diseases caused by plant pathogenic fungi and nematodes. Subtilisin-like serine proteases are considered to play an important role in pathogenesis
Mudassir Iqbal +5 more
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The epidermolytic toxins are serine proteases [PDF]
FEBS Letters, 1990 Certain strains of Staphylococcus aureus usually belonging to phage group II produce epidermolytic toxins (ETA and ETB) which cause intraepidermal splitting in mice, neonates and occasionally adults. Amino acid sequences of ETA and ETB have been reported but the mechanism of epidermolysis remains unknown.
Dancer, Stephanie J. +4 more
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Veterinary Research, 2011 Several alphaherpesviruses breach the basement membrane during mucosal invasion. In the present study, the role of proteases in this process was examined.
Glorieux Sarah +4 more
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