Results 21 to 30 of about 268,204 (256)

The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult

Frontiers in Pharmacology, 2022
Background: Serine proteases are believed to play a key role in the origin of abdominal pain in IBD and IBS. We previously demonstrated a reduction of visceral pain in a post-inflammatory IBS rat model after a single intraperitoneal or intracolonic ...
Hannah Ceuleers, Hannah Ceuleers, Hannah Ceuleers, Nikita Hanning, Nikita Hanning, Michelle De bruyn, Michelle De bruyn, Joris G De Man, Joris G De Man, Heiko U De Schepper, Heiko U De Schepper, Heiko U De Schepper, Qian Li, Liansheng Liu, Steven Abrams, Steven Abrams, Annemieke Smet, Annemieke Smet, Jurgen Joossens, Koen Augustyns, Koen Augustyns, Ingrid De Meester, Ingrid De Meester, Pankaj J Pasricha, Benedicte Y De Winter, Benedicte Y De Winter, Benedicte Y De Winter   +26 more
doaj   +1 more source

Gadolinium-Cyclic 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid-Click-Sulfonyl Fluoride for Probing Serine Protease Activity in Magnetic Resonance Imaging

Molecules, 2023
Serine protease is linked to a wide range of diseases, prompting the development of robust, selective, and sensitive protease assays and sensing methods.
Phuong Tu Huynh, Huy Duc Vu, Junghwa Ryu, Hee Su Kim, Hoesu Jung, Sung Won Youn   +5 more
doaj   +1 more source

Serine proteases [PDF]

IUBMB Life, 2009
AbstractOver one third of all known proteolytic enzymes are serine proteases. Among these, the trypsins underwent the most predominant genetic expansion yielding the enzymes responsible for digestion, blood coagulation, fibrinolysis, development, fertilization, apoptosis, and immunity.
openaire   +3 more sources

Optimization of the Conditions for Extraction of Serine Protease from Kesinai Plant (Streblus asper) Leaves Using Response Surface Methodology

Molecules, 2011
Response surface methodology (RSM) using a central composite design (CCD) was employed to optimize the conditions for extraction of serine protease from kesinai (Streblus asper) leaves.
Md. Zaidul Islam Sarker, Abdul Manap Mohd Yazid, Shuhaimi Mustafa, Amid Mehrnoush   +3 more
doaj   +1 more source

Serine Proteases in Rodent Hippocampus [PDF]

Journal of Biological Chemistry, 1998
Brain serine proteases are implicated in developmental processes, synaptic plasticity, and in disorders including Alzheimer's disease. The spectrum of the major enzymes expressed in brain has not been established previously. We now present a systematic study of the serine proteases expressed in adult rat and mouse hippocampus.
Davies, Ben J., Pickard, Benjamin S., Steel, Muriel, Morris, Richard G. M., Lathe, Richard   +4 more
openaire   +4 more sources

In vitro characterization of jellyfish venom fibrin(ogen)olytic enzymes from Nemopilema nomurai

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Because jellyfish are capable of provoking envenomation in humans, they are considered hazardous organisms. Although the effects of their toxins are a matter of concern, information on the venom components, biological activity and pathological
Seong Kyeong Bae, Hyunkyoung Lee, Yunwi Heo, Min Jung Pyo, Indu Choudhary, Chang Hoon Han, Won Duk Yoon, Changkeun Kang, Euikyung Kim   +8 more
doaj   +1 more source

Identification of a Novel Thermostable Alkaline Protease from Bacillus megaterium-TK1 for the Detergent and Leather Industry

Biology, 2020
An increased need by the green industry for enzymes that can be exploited for eco-friendly industrial applications led us to isolate and identify a unique protease obtained from a proteolytic Bacillus megaterium-TK1 strain from a seawater source.
Tamilvendan Manavalan, Arulmani Manavalan, Shiyamsundar Ramachandran, Klaus Heese   +3 more
doaj   +1 more source

Comparative evolutionary histories of fungal proteases reveal gene gains in the mycoparasitic and nematode-parasitic fungus Clonostachys rosea

BMC Evolutionary Biology, 2018
Background The ascomycete fungus Clonostachys rosea (order Hypocreales) can control several important plant diseases caused by plant pathogenic fungi and nematodes. Subtilisin-like serine proteases are considered to play an important role in pathogenesis
Mudassir Iqbal, Mukesh Dubey, Mikael Gudmundsson, Maria Viketoft, Dan Funck Jensen, Magnus Karlsson   +5 more
doaj   +1 more source

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa

Veterinary Research, 2011
Several alphaherpesviruses breach the basement membrane during mucosal invasion. In the present study, the role of proteases in this process was examined.
Glorieux Sarah, Favoreel Herman W, Steukers Lennert, Vandekerckhove Annelies P, Nauwynck Hans J   +4 more
doaj   +1 more source

Cloning and characterization of Bombyx mandarina serine protease-like protein

浙江大学学报. 农业与生命科学版, 2014
The complementary deoxyribonucleic acid (cDNA) of Bombyx mandarina serine protease-like protein gene was cloned by reverse transcription-polymerase chain reaction (RT-PCR).
Zhang Yongliang, Wu Anquan, Zhao Jinhui
doaj   +1 more source