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Natural serine proteases and their applications in combating amyloid formation [PDF]
ADMET and DMPKBackground and purpose: Amyloidosis is a group of diseases including diabetes type II and neurological disorders, such as Alzheimer’s disease, Parkinson’s disease, prion disease, etc., where a common trait is observed; accumulation of misfolded protein ...
Sanjay Metkar +3 more
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A Double-Edged Sword: Extracellular Serine Proteases as Facilitators of Infection and Mediators of Immunity [PDF]
MoleculesSerine proteases are a class of enzymes that orchestrate an immune response. These proteases can be hijacked by viruses to facilitate entry and spread, while simultaneously supporting the innate immune system in neutralizing pathogens.
Alua Shagirova +4 more
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Extracellular Pneumococcal Serine Proteases Affect Nasopharyngeal Colonization [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Streptococcus pneumoniae has evolved versatile strategies to colonize the nasopharynx of humans. Colonization is facilitated by direct interactions with host cell receptors or via binding to components of the extracellular matrix.
Murtadha Q. Ali +7 more
doaj +2 more sources