Results 131 to 140 of about 183,910 (327)
Advanced Materials Interfaces, EarlyView.Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah +5 more
wiley +1 more source
Visceral Adipose Tissue-Derived Serine Protease Inhibitor (VASPIN) as A Prognostic Marker in Systemic Hypertension [PDF]
, 2022 Hanaa Fathey +3 more
openalex +1 more source
HPLC-MS characterisation of chelate modified somatropin [PDF]
, 2010 Somatropin is a recombinant human growth hormone, consisting of 191 amino acids. This protein is clinically used in children and adults with inadequate endogenous growth hormone to stimulate a normal bone and muscle growth.
De Spiegeleer, Bart +5 more
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Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao +6 more
wiley +1 more source
Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration
Advanced Science, EarlyView.Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin +7 more
wiley +1 more source
Advanced Science, EarlyView.Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu +6 more
wiley +1 more source
Production, purification and characterization of a thermotolerant alkaline serine protease from a novel species Bacillus caseinilyticus [PDF]
, 2016 Thirumala Mothe +1 more
openalex +1 more source
Novel serine proteases in spinach plants [PDF]
, 1985 分泌タンパク質や細胞内小器官に局在するタンパク質の多くは、前駆体タンパク質として合成され、合成および移送の過程で限定分解を受けた後、成熟タンパク質として機能することが知られている。この限定分解に関与するproteasesの研究は動物・植物を問わずほとんど進展をみていない現状にある。本研究はホウレンソウを用いて、細胞内に微量に存在する膜結合性のserine proteasesを検出し、あわせて酵素としての性質を明らかにしたものであり、4章から成る。 ･･･Thesis--University of ...
Satoh Shinobu, 佐藤 忍
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Advanced Science, EarlyView.Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren +9 more
wiley +1 more source
Advanced Science, EarlyView.PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li +17 more
wiley +1 more source