Results 191 to 200 of about 541,956 (367)

Clip-domain serine proteases as immune factors in insect hemolymph.

Current Opinion in Insect Science, 2015
M. Kanost, Haobo Jiang
semanticscholar   +1 more source

Engineered Dual‐Function Antibody‐Like Proteins to Combat SARS‐CoV‐2‐Induced Immune Dysregulation and Inflammation

Advanced Science, EarlyView.
Engineered antibody‐like proteins block the SARS‐CoV‐2 spike protein from binding to host receptors and suppress immune overactivation through an MBL‐based scaffold. These dual‐function proteins effectively alleviate inflammation, complement activation, and lung injury, offering a promising therapeutic strategy against severe COVID‐19 and its ...
Yizhuo Wang, Chenwu Bai, Kerui Hou, Zhen Zhang, Ming Guo, Xin Wang, Fan Yang, Xin Liu   +7 more
wiley   +1 more source

The role of the serine protease active site in the mode of action of epidermolytic toxin of Staphylococcus aureus [PDF]

, 1991
M Redpath
openalex   +1 more source

Sequence conservation, phylogenetic relationships, and expression profiles of nondigestive serine proteases and serine protease homologs in Manduca sexta.

Insect Biochemistry and Molecular Biology, 2015
Xiaolong Cao, Yan He, Yingxia Hu, Xiufeng Zhang, Yang Wang, Z. Zou, Yunru Chen, G. Blissard, M. Kanost, Haobo Jiang   +9 more
semanticscholar   +1 more source

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

Advanced Science, EarlyView.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen, Wei Bao, Kaiyuan Liu, Na Jing, Genyu Du, Luyao Jiang, Qian You, Yingchao Zhang, Penghui Xu, Chaping Cheng, Nan Wang, Xialian Xi, Mingyue Wang, Yiyun Liu, Jinming Wang, Huifang Zhao, Shilei Zhang, Dinglan Wu, Chi‐Fai Ng, Jiahua Pan, Wei Xue, Wei‐Qiang Gao, Pengcheng Zhang, Kai Zhang, Helen He Zhu   +24 more
wiley   +1 more source

Type II Transmembrane Serine Proteases as Modulators in Adipose Tissue Phenotype and Function. [PDF]

Biomedicines, 2023
Wu Q, Li S, Zhang X, Dong N.
europepmc   +1 more source

Evolution of Catalysis in the Serine Proteases

Cold Spring Harbor Symposia on Quantitative Biology, 1987
Charles S. Craik, Jeffrey N. Higaki, B.W. Gibson   +2 more
openaire   +3 more sources

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

The Activity of Metalloproteases and Serine Proteases in Various Organs after Leiurus macroctenus Envenomation. [PDF]

J Toxicol, 2023
Gunas V, Maievskyi O, Raksha N, Vovk T, Savchuk O, Shchypanskyi S, Gunas I.   +6 more
europepmc   +1 more source

Crystallographic refinement by incorporation of molecular dynamics: thermostable serine protease thermitase complexed with eglin c

, 1989
Piet Gros, M. Fujinaga, B.W. Dijkstra, K.H. Kalk, Wim G. J. Hol   +4 more
openalex   +1 more source