Results 221 to 230 of about 541,956 (367)

Cloning and characterization of an extracellular temperature-labile serine protease gene fromAeromonas hydrophila [PDF]

open access: bronze, 1991
O Rivero   +4 more
openalex   +1 more source

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

open access: yesAdvanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai   +13 more
wiley   +1 more source

A Genetically Encoded Homocysteine Precursor to Probe Protein Active Sites and to Addict Escherichia coli to a Noncanonical Amino Acid Directly Involved in Catalysis

open access: yesAngewandte Chemie, EarlyView.
A new genetically encoded amino acid is chemically converted into homocysteine (Hcy) under mild conditions to probe and to activate protein active sites. Surprisingly, Hcy can replace cysteine or serine residues in several enzymes. Its potential for a widespread use in proteins is further underlined by rendering Escherichia coli dependent on Hcy ...
Clara Dunker, Henning D. Mootz
wiley   +2 more sources

Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. [PDF]

open access: yesPLoS Genet, 2023
Nakano S   +10 more
europepmc   +1 more source

The 3(rd) International Symposium on Kallikreins and Kallikrein-Related Peptidases [PDF]

open access: yes, 2010
Fritz, Hans   +3 more
core   +1 more source

Structural Basis of GABAB Receptor Activation during Evolution

open access: yesAdvanced Science, EarlyView.
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou   +14 more
wiley   +1 more source

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