Results 231 to 240 of about 541,956 (367)
Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky+3 more
wiley +1 more source
Critical role of lectin pathway mediated by MBL-associated serine proteases in complement activation for the pathogenesis in systemic lupus erythematosus. [PDF]
Asanuma Y+6 more
europepmc +1 more source
Sequence, Purification, and Cloning of an Intracellular Serine Protease, Quiescent Cell Proline Dipeptidase [PDF]
Robert Underwood+6 more
openalex +1 more source
Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source
S. aureus Eap is a polyvalent inhibitor of neutrophil serine proteases. [PDF]
Mishra N+6 more
europepmc +1 more source
Role of Serine Proteases at the Tumor-Stroma Interface. [PDF]
Tagirasa R, Yoo E.
europepmc +1 more source
Two Lineages of Mannose-Binding Lectin-Associated Serine Protease (MASP) in Vertebrates [PDF]
Yuichi Endo+7 more
openalex +1 more source