Results 251 to 260 of about 541,956 (367)

Endogenous Serine Protease Inhibitor Modulates Epileptic Activity and Hippocampal Long-Term Potentiation [PDF]

, 1997
Andreas Lüthi, Herman van der Putten, Florence Botteri, Isabelle M. Mansuy, Marita Meins, Uwe Frey, Gilles Sansig, C. Portet, Markus Schmutz, Markus Schröder, Cordula Nitsch, Jean-Paul Laurent, Denis Monard   +12 more
openalex   +1 more source

Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling

Angewandte Chemie International Edition, Accepted Article.
Controlling protein‐protein interactions is critical for dissecting signaling pathways, especially those initiated by ligand‐receptor interactions which alter receptor oligomerization and drive downstream signaling cascades. Traditional methods for driving protein‐protein complexes are using antibodies that face limitations in terms of stoichiometry ...
Johannes Broichhagen, Michael Trumpp, Blaise Gatin-Fraudet, Kjell Bruckmann, Wiktor Burdzinski, Kilian Roßmann, Joshua Levitz, Petra Knaus, Jerome Jatzlau   +8 more
wiley   +1 more source

Aeruginosin 525 (AER525) from Cyanobacterium Aphanizomenon Sp. (KUCC C2): A New Serine Proteases Inhibitor. [PDF]

Mar Drugs
Overlingė D, Cegłowska M, Konkel R, Mazur-Marzec H.   +3 more
europepmc   +1 more source

Inhibition of Serine Proteases as a Novel Therapeutic Strategy for Abdominal Pain in IBS. [PDF]

Front Physiol, 2022
Decraecker L, Boeckxstaens G, Denadai-Souza A.   +2 more
europepmc   +1 more source

Site-directed mutagenesis suggests close functional relationship between a human rhinovirus 3C cysteine protease and cellular trypsin-like serine proteases.

, 1990
Keat-Chye Cheah, Louis E.-C. Leong, Alan G. Porter   +2 more
openalex   +1 more source

Evidence that HetR protein is an unusual serine-type protease [PDF]

, 1998
Ruanbao Zhou, Xingcheng Wei, Nan Jiang, Huiguang Li, Yuqing Dong, Kuo-L. Hsi, Jindong Zhao   +6 more
openalex   +1 more source

Serine Proteases Degrade Airway Mucins in Cystic Fibrosis

Infection and Immunity, 2011
M. Henke, G. John, Christina Rheineck, S. Chillappagari, L. Naehrlich, B. Rubin   +5 more
semanticscholar   +1 more source

Redirecting the Peptide Cleavage Causes Protease Inactivation

Angewandte Chemie International Edition, EarlyView.
Cysteine proteases catalyze substrate cleavage by a two‐step acyl transfer mechanism. Newly designed peptidic inhibitors of human cathepsin B with N‐terminal carbamate warheads undergo a redirected cleavage and generate non‐canonical covalent complexes.
Christian Breuer, Jim Küppers, Anna‐Christina Schulz‐Fincke, Anna Heilos, Carina Lemke, Petra Spiwoková, Janina Schmitz, Laura Cremer, Marta Frigolé‐Vivas, Michael Lülsdorff, Matthias D. Mertens, Filip Wichterle, Miloš Apeltauer, Martin Horn, Erik Gilberg, Norbert Furtmann, Jürgen Bajorath, Ulrike Bartz, Bernd Engels, Michael Mareš, Michael Gütschow   +20 more
wiley   +1 more source

Entamoeba histolytica-induced NETs are highly cytotoxic on hepatic and colonic cells due to serine proteases and myeloperoxidase activities. [PDF]

Front Immunol
Jorge-Rosas F, Díaz-Godínez C, García-Aguirre S, Martínez-Calvillo S, Carrero JC.   +4 more
europepmc   +1 more source

A multidrug resistance transporter/serine protease gene is required for prestalk specialization in Dictyostelium. [PDF]

, 1995
Gad Shaulsky, Adam Kuspa, William F. Loomis   +2 more
openalex   +1 more source