Results 301 to 310 of about 541,956 (367)

Inhibition of Amyloid β-Protein Production in Neural Cells by the Serine Protease Inhibitor AEBSF

, 1996
Martin Citron, Thekla S. Diehl, Anja Capell, Christian Haass, David B. Teplow, Dennis J. Selkoe   +5 more
openalex   +1 more source

Advancing the Exploration of the Ubiquitin‐like Protein FUBI with Synthetic Chemical Tools

ChemBioChem, EarlyView.
This study unveils a novel synthetic platform by solid‐phase peptide synthesis for generating FUBI‐based chemical tools to investigate FUBIylation, a poorly understood ubiquitin‐like signaling process linked to cancer. By employing these innovative probes, we uncover novel FUBI interactors, paving the way for transformative insights into FUBI biology ...
Francesca D’Amico, Cami M. P. Talavera Ormeño, Shivanganie Poeran, Jimmy Akkermans, Rayman T. N. Tjokrodirijo, Bharath Sampadi, Peter van Veelen, Aysegul Sapmaz, Monique P. C. Mulder   +8 more
wiley   +1 more source

Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar (Lepisosteus oculatus). [PDF]

Int J Mol Sci
Valentini P, Akula S, Alvarado-Vazquez A, Hallgren J, Fu Z, Racicot B, Braasch I, Thorpe M, Hellman L.   +8 more
europepmc   +1 more source

Sequence analysis and regulation of a gene encoding a cuticle-degrading serine protease from the nematophagous fungus Arthrobotrys oligospora

, 1996
Jens Åhman, Bo Ek, Lars Rask, Anders Tunlid   +3 more
openalex   +1 more source

C13‐Deacylase from Nocardioides albus Resp. Streptomyces sp., Catalyzing Side Chain Hydrolysis on the Taxane Core

ChemCatChem, EarlyView.
An enzyme that has been identified and characterized as capable of hydrolyzing paclitaxel (Taxol), a key anticancer drug derived from Pacific yew (Taxus brevifolia) has been identified. Molecular docking (MD) simulations map the catalytic triad and critical residues that drive substrate‐enzyme interactions. The findings indicate the catalytic potential
Jinfen Su, Eugen Schell, Thomas Heine, Marion B. Ansorge‐Schumacher   +3 more
wiley   +1 more source

Plasma levels of mannan-binding lectin-associated serine proteases are increased in type 1 diabetes patients with insulin resistance. [PDF]

Clin Exp Immunol
Kietsiriroje N, Scott GE, Ajjan RA, Brôz J, Schroeder V, Campbell MD.   +5 more
europepmc   +1 more source

A signaling pathway, independent of the oxidative burst, that leads to hypersensitive cell death in cultured tobacco cells includes a serine protease

, 1999
Akira Yano, Kaoru Suzuki, Hideaki Shinshi   +2 more
openalex   +1 more source

Advancing Biocatalysis: Using Siloxanes to Solubilize and Stabilize Enzymes in Organic Solvents

ChemCatChem, EarlyView.
Biocatalysis offers an attractive route in the development of more sustainable approaches in silicon chemistry. Given the propensity for enzymes to operate optimally in an aqueous environment there are obvious challenges to incorporating biocatalysts in organic solvents.
Najibeh Alizadeh, Zain Ahmed, Paul M. Zelisko   +2 more
wiley   +1 more source

The Cortical Granule Serine Protease CGSP1 of the Sea Urchin, Strongylocentrotus purpuratus, Is Autocatalytic and Contains a Low-Density Lipoprotein Receptor-like Domain

, 1999
Sheila A. Haley, Gary M. Wessel
openalex   +1 more source

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source